Molecular neurology
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Stephen G Waxman
- ناشر : Burlington, MA : Elsevier Academic Press
- چاپ و سال / کشور: 2007
- شابک / ISBN : 9780123695093
Description
Genetics as a tool in neurology -- Neurology and genomic medicine -- Mitochondrial function and dysfunction in the nervous system -- Neuronal channels and receptors -- Protein misfolding, chaperone networks, and the heat shock response in the nervous system -- Metabolic biopsy of the brain -- Gene therapy approaches in neurology -- Programmed cell death and its role in neurological disease -- Developmental neurology: a molecular perspective -- Metabolic diseases of the nervous sytsem -- Genetic disorders of neuromuscular development -- Molecular mechanisms of ischemic brain disease -- Hemorrhagic brain disease -- The Dawn of molecular and cellular therapies for traumatic spinal cord injury -- Parkinson disease: molecular insights -- The Molecular basis of Alzheimer's disease -- Polyglutamine disorders including Huntington's disease -- Friedreich's ataxia and related DNA loss-of-function disorders -- DYT1, an inherited dystonia -- Motor neuron disease: amyotrophic lateral sclerosis -- Genetic disorders of the autonomic nervous system -- Multiple sclerosis as a neurodegenerative disease -- Acquired epilepsy: cellular and molecular mechanisms -- Genetic epilepsies -- Tourette's syndrome -- Disorders of sleep and circadian rhythms -- Chronic pain as a molecular disorder -- Migraine as a cerebral ionopathy with impaired central sensory processing -- Myelin protein zero and CMT 1 B: a tale of two phenotypes -- Demyelinating diseases: immunological mechanisms in the pathogenesis of multiple sclerosis -- Autoimmune and genetic disorders of the neuromuscular junction and motor nerve terminal -- Paraneoplastic neurologic syndromes -- Mitochondrial disorders -- Molecular neurology of HIV-1 infection and AIDS
Presents the principles and disease examples relevant to molecular neurology. This book describes the molecular aspects of neurological disorders. It provides an introduction to neurological disorders for basic scientists. It is useful for those studying the molecular basis of neurology, or developing therapies in neurology
