Handbook of epigenetics : the new molecular and medical genetics

Handbook of epigenetics : the new molecular and medical genetics

  • نوع فایل : کتاب
  • زبان : انگلیسی
  • مؤلف : Trygve O Tollefsbol
  • ناشر : Amsterdam ; Boston : Elsevier/Academic Press
  • چاپ و سال / کشور: 2011
  • شابک / ISBN : 9780123757098

Description

FUNCTIONS OF EPIGENETICSEVOLUTIONARY EPIGENETICSEPIGENETIC EPIDEMIOLOGYEPIGENETICS AND HUMAN DISEASESEPIGENETIC THERAPYMechanisms of DNA Methylation, Methyl-CpG Recognition, and Demethylation in MammalsA STRUCTURAL FRAGMENT OF Dnmt1REPLICATION-COUPLED CROSSTALK BETWEEN DNA METHYLATION AND HISTONE MODIFICATIONSAnalysis of Gene-specific DNA MethylationMethods for Assessing Genome-wide DNA MethylationMouse Models of Epigenetic InheritanceNUTRIENTS INVOLVED IN ONE-CARBON METABOLISM1BACTERIA AND EPIGENETIC MODIFICATION IN THE GUT
Epigenetics : the new science of genetics --

[pt.] I. Molecular mechanisms of epigenetics. Mechanisms of DNA methylation, methy-CpG recognition, and demethylation in mammals --

Mechanisms of histone modifications --

[pt.] II. Additional epigenetic processes. The epigenetics of non-coding RNA --

Prions and prion-like phenomena in epigenetic inheritance --

Chromosomal position effects and gene variegation : impact in pathologies --

Polycomb mechanisms and epigenetic control of gene activity --

[pt.] III. Epigenetic technology. Analysis of gene-specific DNA methylation --

Methods for assessing genome-wide DNA methylation --

Methylation of lysine-9 of histone H3 : role of heterochromatin modulation and tumorigenesis --

Chromatin modifications distinguish genomic features and physical organization of the nucleus --

Assessing epigenetic information --

[pt.] IV. Model organisms of epigenetics. Epigenetics of eukaryotic microbes --

Drosophila epigenetics --

Mouse models of epigenetic inheritance --

Epigenetic regulatory mechanisms in plants --

[pt.] V. Metabolism and epigenetics. Metabolic regulation of DNA methylation in mammals --

Dietary and metabolic compounds affecting chromatin dynamics/remodeling --

[pt.] VI. Functions of epigenetics. Epigenetics, stem cells, and cellular differentiation --

Epigenetic basis of skeletal muscle regeneration --

Epigenetics of X chromosome inactivation --

Genomic imprinting --

Epigenetics of memory processes --

Transgenerational epigenetics --

Aging epigenetics --

[pt.] VII. Evolutionary epigenetics. Epigenetics in adaptive evolution and development : the interplay between evolving species and epigenetic mechanisms --

[pt.] VIII. Epigenetic epidemiology. The effects of diet on epigenetic processes --

Environmental agents and epigenetics --

Impact of microbial infections on the human epigenome and carcinogenesis --

DNA methylation profiles in the 5'-upstream region of the human FMR1 promoter and in an adenovirus transgenome --

Population pharmacoepigenomics --

[pt.] IX. Epigenetics and human disease. Cancer epigenetics --

The role of epigenetics in immune disorders --

Epigenetics of brain disorders --

Complex metabolic syndromes and epigenetics --

Imprinting disorders in humans --

[pt.] X. Epigenetic therapy. Clinical applications of histone deacetylase inhibitors.
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