Parvoviruses

PART 1 BIOLOGY OF THE VIRUS FAMILY 01 Section A Virus groups and evolution of the family 03 1 The evolution of parvovirus taxonomy 05 Peter Tattersall 2 The genus Dependovirus 15 Dawn E. Bowles, Joseph E. Rabinowitz, and R. Jude Samulski 3 The genus Erythrovirus 25 Kevin E. Brown 4 Autonomous parvovirus variation and evolution 47 Colin R. Parrish 5 Evolution of densoviruses 55 P. Tijssen, H. Bando, Y. Li, F.-X. Jousset, Z. Zádori, G. Fédière, M. El-Far, J. Szelei, and M. Bergoin Section B The rugged virion 69 6 Introduction 71 Susan F. Cotmore and Peter Tattersall 7 Structure and organization of the viral genome 73 Susan F. Cotmore and Peter Tattersall 8 Phospholipase A2 domains in structural proteins of parvoviruses 95 P. Tijssen, J. Szelei, and Z. Zádori 9 Atomic structure of viral particles 107 Michael S. Chapman and Mavis Agbandje-McKenna 10 Correlating structure with function in the viral capsid 125 Mavis Agbandje-McKenna and Michael S. Chapman Section C Viral life cycles: molecular interactions between virus and host cell 141 11 The parvovirus life cycle: an introduction to molecular interactions important for infection 143 Matthew D. Weitzman 12 Cell infection processes of autonomous parvoviruses 157 Maija Vihinen-Ranta and Colin R. Parrish 13 Looking down the rabbit hole: understanding the binding, entry, and trafficking patterns of AAV particles in the cell 165 John A. Chiorini14 A rolling-hairpin strategy: basic mechanisms of DNA replication in the parvoviruses 171 Susan F. Cotmore and Peter Tattersall 15 Replication of adeno-associated virus DNA 189 Peter Ward 16 Site-specific integration by adeno-associated virus 213 Nathalie Dutheil and R. Michael Linden 17 Latent infection of the host cell by AAV and its disruption by helper viruses 237 Roland A. Owens 18 Parvovirus RNA processing strategies 253 Jianming Qiu, Yuko Yoto, Gregory Tullis, and David J. Pintel 19 Regulation of non-structural protein functions by differential synthesis, modification and trafficking 275 Jürg P.F. Nüesch 20 Synthesis, post-translational modification and trafficking of the parvovirus structural polypeptides 291 Noelia Valle, Laura Riolobos, and Jose M. Almendral 21 Molecular interactions involved in assembling the viral particle and packaging the genome 305 J.A. Kleinschmidt and J.A. King PART 2 PATHOGENESIS AND BIOLOGY OF PARVOVIRUS INFECTION 321 22 Pathogenesis of parvovirus infections 323 Marshall E. Bloom and Jonathan R. Kerr 23 Parvovirus host range, cell tropism and evolution – studies of canine and feline parvoviruses, minute virus of mice, porcine parvovirus, and Aleutian mink disease virus 343 Colin R. Parrish and Karsten Hueffer 24 Immunology of human erythrovirus infection 351 Klaus Hedman, Rauli Franssila, Leena Kaikkonen, Kati Hokynar, Laura Kakkola, and Maria Söderlund-Venermo 25 Parvovirus oncosuppression 365 Jan J. Cornelis, Laurent Deleu, Ute Koch, and J. Rommelaere PART 3 SPECIFIC PARVOVIRUS INFECTIONS AND ASSOCIATED DISEASE 379 26 Human dependovirus infection 381 Jonathan R. Kerr and R. Michael Linden 27 Human and primate erythrovirus infections and associated disease 385 Jonathan R. Kerr and Susanne Modrow 28 Rodent parvovirus infection and associated disease 417 Lisa J. Ball-Goodrich and Robert O. Jacoby 29 Pathogenesis of feline panleukopenia virus and canine parvovirus 429 Colin R. Parrish 30 Porcine parvovirus 435 J. Szelei, Z. Zádori, and P. Tijssen 31 Waterfowl parvoviruses 447 Z. Zádori, J. Szelei, I. Kiss, and P. Tijssen 32 Aleutian mink disease parvovirus 457 Sonja M. Best and Marshall E. Bloom 33 Minute virus of canines (canine minute virus) – the virus and its diseases 473 Colin R. Parrish 34 Bovine parvovirus 479 Laura E. Via, Catherine Mainguy, Stanley Naides, and Muriel Lederman 35 Shrimp parvoviruses 487 Timothy W. Flegel PART 4 USE OF PARVOVIRUSES AS GENE THERAPY AND VACCINE DELIVERY VECTORS 495 36 Adeno-associated virus vectors and biology of gene delivery 497 Barrie J. Carter 37 Clinical development with adeno-associated virus vectors 499 Barrie J. Carter38 Mechanism of recombinant adeno-associated virus transduction 511 Ziying Yan, Dongsheng Duan, and John F. Engelhardt 39 Expanding the capacity of AAV vectors 525 Dongsheng Duan, Ziying Yan, and John F. Engelhardt 40 Tailoring of the AAV capsid: designing the second generation vector 533 Nicholas Muzyczka and Kenneth H. Warrington Jr 41 rAAV vectors for gene targeting 543 Toni Cathomen 42 rAAV gene transfer to the liver 551 Terence R. Flotte 43 AAV vectors for retinal gene therapy 559 Seok-Hong Min, Astra Dinculescu, Lyudmyla Glushakova, and William W. Hauswirth 44 Helper-independent parvoviruses as gene therapy and vaccine delivery vectors 571 Jan J. Cornelis and Christiane Dinsart