Cannabinoids and the Brain.
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Attila Kofalvi
- ناشر : Dordrecht : Springer
- چاپ و سال / کشور: 2008
- شابک / ISBN : 9780387743493
Description
Front Matter; An Historical Introduction to the Endocannabinoid and Endovanilloid Systems; Biosynthesis of Anandamide and 2-Arachidonoylglycerol; Removal of Endocannabinoids by the Body: Mechanisms and Therapeutic Possibilities; Other Cannabimimetic Lipid Signaling Molecules; CB1 Cannabinoid Receptors: Molecular Biology, Second Messenger Coupling and Polarized Trafficking in Neurons; CB2 Cannabinoid Receptors: Molecular, Signaling, and Trafficking Properties; CB1 and CB2 Receptor Pharmacology; Functional Molecular Biology of the TRPV1 Ion Channel. Alternative Interacting Sites and Novel Receptors for Cannabinoid LigandsAnatomical Distribution of Receptors, Ligands and Enzymes in the Brain and in the Spinal Cord: Circuitries and Neurochemistry; Endocannabinoids at the Synapse: Retrograde Signaling and Presynaptic Plasticity in the Brain; Endocannabinoid Functions in Neurogenesis, Neuronal Migration, and Specification; Cannabinoids in the Management of Nausea and Vomiting; Endocannabinoids in Energ.
Endocannabinoids control most of the body functions, and in the brain, they modulate neurotransmission, synaptic plasticity, confer neuroprotection, control metabolism, neuro- and neuritogenesis, survival, cognitive and motor functions as well as a plethora of other higher-order brain functions. Their fruitful therapeutic potential is recognized by cannabinoid researchers and pharmaceutical companies, respectively. The aim of this book is to help clinicians, neuroscientists, as well as students, understand the significance of the endocannabinoid system. This book, however, also will be very us.
