Multifunctional pharmaceutical nanocarriers

Multifunctional Pharmaceutical Nanocarriers: Development of the Concept .................................................................................................. 1 Vladimir P. Torchilin Multifunctional Polymeric Nanosystems for Tumor-Targeted Delivery .......................................................................... 33 Padmaja Magadala, Lilian E. van Vlerken, Aliasgar Shahiwala, and Mansoor M. Amiji Nanogels as Pharmaceutical Carriers ............................................................ 67 Alexander V. Kabanov and Serguei V. Vinogradov Multifunctional Water-Soluble Polymers for Drug Delivery ....................... 81 Huaizhong Pan and Jindřich Kopeček “Smart” pH-Responsive Carriers for Intracellular Delivery of Biomolecular Drugs ..................................................................................... 143 P.S. Stayton and A.S. Hoffman Stimuli-Sensitive Nanosystems: For Drug and Gene Delivery ............................................................................................ 161 Han Chang Kang, Eun Seong Lee, Kun Na, and You Han Bae Functionalized Dendrimers as Nanoscale Drug Carriers ................................................................................................... 201 Rohit Kolhatkar, Deborah Sweet, and Hamidreza Ghandehari Biodegradable Multitargeting Nanoconjugates for Drug Delivery ............................................................................................. 233 Julia Y. Ljubimova, Keith L. Black, Alexander V. Ljubimov, and Eggehard Holler viiPharmaceutical Micelles: Combining Longevity, Stability, and Stimuli Sensitivity ..................................................................................... 263 Myrra G. Carstens, Cristianne J.F. Rijcken, Cornelus F. van Nostrum, and Wim E. Hennink Multifunctional Nanotherapeutics for Cancer .............................................. 309 T. Minko, J.J. Khandare, A.A. Vetcher, V.A. Soldatenkov, O.B. Garbuzenko, M. Saad, and V.P. Pozharov Charge Modification of Pharmaceutical Nanocarriers: Biological Implications .................................................................................... 337 N. Nafee, M. Schneider, and C.-M. Lehr Funtionalization of Pharmaceutical Nanocarriers for Mitochondria-Targeted Drug and DNA Delivery ................................... 363 Volkmar Weissig, Sarathi Boddapati, Gerard D’Souza, and Richard W. Horobin Multifunctional Magnetic Nanosystems for Tumor Imaging, Targeted Delivery, and Thermal Medicine .................................................... 381 Dattatri Nagesha, Harikrishna Devalapally, Srinivas Sridhar, and Mansoor Amiji Nanosystems for Multimodality In vivo Imaging ......................................... 409 Jinzi Zheng, David A. Jaffray, and Christine Allen Long-Circulating Liposomes with Attached Diagnostic Moieties: Application for Gamma and MR Imaging .................................................... 431 William Phillips, Beth Goins, and Ande Bao Index .................................................................................................................. 457 viii Contents