Handbook of disease burdens and quality of life measures

Part 1 Instruments and Methodological Aspects . . . . . . . . . . . 1 Part 1.1 Instruments Used in the Assessment of Disease Impact . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1 The International Classification of Functioning, Disability and Health: A Tool to Classify and Measure Functioning . . . . . . . . . . . . . . . . . . . . . . . . 3 G. Stucki . N. Kostanjsek . A. Cieza 2 The Keele Assessment of Participation . . . . . . . . . . . . . . . . . . . . . . . . . . . 35 R. Wilkie 3 The Global Person Generated Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59 F. Martin . L. Camfield . D. Ruta 4 The Total Illness Burden Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73 S. Greenfield . J. Billimek . S. H. Kaplan 5 The EQ-5D Health-Related Quality of Life Questionnaire . . . . . . . . . . . . . 87 N. Gusi . P. R. Olivares . R. Rajendram 6 The University of Washington Quality of Life Scale . . . . . . . . . . . . . . . . .101 S. N. Rogers . D. Lowe 7 Comparison of Three Quality of Life Questionnaires in Urinary Incontinence . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .129 Ja Hyeon Ku . Seung-June Oh 8 Overview of Instruments Used to Assess Quality of Life in Dentistry . . . .145 C. McGrath . S. N. Rogers 9 SQOR-V: A Patient Reported Outcome Specifically Dedicated to Chronic Venous Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .161 J.-J. Guex . S. E. Zimmet . S. Boussetta . C. Taieb10 The Uniscale Assessment of Quality of Life: Applications to Oncology . . .179 E. Ballatori . F. Roila . B. Ruggeri . A. A. Bruno . S. Tiberti . F. di Orio 11 The Bone Metastases Quality of Life Questionnaire . . . . . . . . . . . . . . . . .195 X. Badia . A. Vieta . M. Gilabert 12 The Impact of Weight on Quality of Life Questionnaire . . . . . . . . . . . . . .209 J. Manwaring . D. Wilfley 13 The Quality in Later Life Questionnaire . . . . . . . . . . . . . . . . . . . . . . . . . .227 S. Evans 14 The MacDQOL Individualized Measure of the Impact of Macular Disease on Quality of Life . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .247 Jan Mitchell . Alison Woodcock . Clare Bradley 15 Development and Assessment of Chinese General Quality of Life Instrument . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .265 Y. Wu . G. Xie 16 The Japanese Version of the EORTC Quality of Life Questionnaire . . . . . .285 G. To´th . M. Tsukuda Part 1.2 Contemporary Issues in Assessment . . . . . . . . . . . . 311 17 Calculating QALYs and DALYs: Methods and Applications to Fatal and Non-Fatal Conditions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .313 F. Sassi 18 Accuracy of Death Certifications and the Implications for Studying Disease Burdens . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .329 J. R. Pierce . A. V. Denison 19 Completeness and Accuracy of Death Dates and the Implications for Studying Disease Burdens: Focus on Alternative Data Sources . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .345 Min-Woong Sohn . Elissa Oh 20 Utility Scores for Comorbid Conditions: Methodological Issues and Advances . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .359 C. N. McIntosh 21 Subjective Quality of Life Measures – General Principles and Concepts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .381 C. L. K. Lam 22 Standard Expected Years of Life Lost as a Measure of Disease Burden: An Investigation of Its Presentation, Meaning and Interpretation . . . . . .401 R. J. MarshallPart 2 Disease Burdens and Economic Impacts . . . . . . . . . . . 415 Part 2.1 General Aspects, Geographical Aspects, Pathologies and Metabolic Disorders . . . . . . . . . . . 415 23 Health-Adjusted Life Expectancy: Concepts and Estimates . . . . . . . . . . . .417 J. A. Labbe 24 Individual Disability-Adjusted Life Year: A Summary Health Outcome Indicator Used for Prospective Studies . . . . . . . . . . . . . . . . . . . . . . . . . . .425 P. Zhang . M. Woodward . J. Shen . Y. Wu 25 Integration of Quality of Life and Survival for Comparative Risk/Outcome Assessment in Healthcare Industry . . . . . . . . . . . . . . . . . .437 J.-D. Wang . J.-S. Hwang 26 Disability-Adjusted Life Years in Occupational Injuries and Accidents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .447 M. Concha-Barrientos . J. Labbe¢¥ Cid 27 The Income-Associated Burden of Disease in the United States . . . . . . . .459 P. Muennig . M. Gold . E. Lubetkin . H. Jia 28 Financial Burdens and Disability-Adjusted Life Years in Los Angeles County . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .473 G. F. Kominski . P. A. Simon . A. Y. Ho . J. E. Fielding 29 Burden of Disease Between Two Time Frames: Mexico Perspectives . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .483 G. Rodriguez-Abrego . J. Escobedo-de la Pen.a . R. B. Zurita Garza . T. Ram©¥¢¥rez-Sa¢¥nchez 30 East/West Differences in Health in Europe: Rates, Expectancies and DALYs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .505 J. Powles . H. Gouda 31 The Burden of Neglected Diseases in Developing Countries . . . . . . . . . . .517 A. Boutayeb 32 The Burden of Communicable and Non-Communicable Diseases in Developing Countries . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .531 A. Boutayeb 33 Economic Evaluation of Health Interventions: Tanzania Perspectives . . . .547 B. Robberstad . Yusuf Hemed 34 The Burden of Disease and Injury in Serbia . . . . . . . . . . . . . . . . . . . . . . .587 S. Jankovic¢¥ . H. Vlajinac . V. Bjegovic¢¥ . J. Marinkovic¢¥ . S. S ¢§ ipetic¢¥-Grujicic¢¥ . Markovic¢¥-Denic¢¥ . N. Kocev . M. S ¢§ antric¢¥-Milic¢¥evic¢¥ . Z. Terzic¢¥-S¢§upic¢¥ . N. Maksimovic¢¥ . U. Laaser Table of Contents ix35 Disease Burdens and Disability-Adjusted Life Years in Aboriginal and Non-Aboriginal Populations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .603 Y. Zhao 36 The Relationship Between the National Health Insurance Expenditures and the Burden of Disease Measures in the Iran . . . . . . . . . . . . . . . . . . . .629 M. Russel . H. R. Jamshidi 37 The Burden of Maternal Mortality and Morbidity in the United States and Worldwide . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .647 C. T. Lang . J. C. King 38 The Financial Implications of Pancreas Transplant Complications . . . . . .661 J. A. Cohn . M. J. Englesbe 39 The Use of Pharmacoepidemiological Databases to Assess Disease Burdens: Application to Diabetes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .671 H. Stّvring 40 Years of Life Lost Due to Air Pollution in Switzerland: A Dynamic Exposure-Response Model . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .685 M. Ro¨o¨sli 41 Quantification of Deaths and DALYs Due to Chronic Exposure to Arsenic in Groundwaters Utilized for Drinking, Cooking and Irrigation of Food-Crops . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .701 D. A. Polya . D. Mondal . A. K. Giri Part 2.2 Early Life Stages and Aging . . . . . . . . . . . . . . . . . . . . 729 42 Disability-Adjusted Life Years in Children and Adolescents in Europe . . .731 F. Valent . S. Di Bartolomeo 43 Disease Burden of Diarrheal and Respiratory Disorders in Children: Hong Kong Perspectives . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .751 E. A. S. Nelson 44 Burden of Disease in Elderly Mexican Population . . . . . . . . . . . . . . . . . . .763 B. Rico-Verd‎´n . G. Rodriguez-Abrego . I. Villasenکor-Ruiz . J. L. Torres-Cosme Volume 2 Part 2.3 Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 783 45 Years of Life Lost from Cancer and Applications to Research Funding . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .785 N. G. Burnet . S. J. Jefferies . F. P. Treasure46 Worldwide Burden of Gynecological Cancer . . . . . . . . . . . . . . . . . . . . . . .803 R. Sankaranarayanan . J. Ferlay 47 Years of Life Lost from Lung, Stomach, Liver and Cervical Cancers: An Evaluation of the Top Cancer Killers . . . . . . . . . . . . . . . . . . . . . . . . . .825 B. Y. Goldstein . F. I. Bray . D. M. Parkin . J. W. Sellors . Z. F. Zhang 48 Burden of Cancer in Serbia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .843 H. Vlajinac . S. Sipetic-Grujicic . S. Jankovic . L. Markovic-Denic . J. Marinkovic 49 The Disease Burden of Mastectomy: Turkish Perspective and Impact on the Patient and Family . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .865 S. O¨ zkan . M. O¨ zkan . V. O¨ zmen . Z. Armay 50 The Burden of Chemotherapy Induced Nausea and Vomiting on Patients’ Daily Lives: Italian Perspectives . . . . . . . . . . . . . . . . . . . . . . . . .885 E. Ballatori . F. Roila . B. Ruggeri . A. A. Bruno . S. Tiberti . F. di Orio Part 2.4 Cardiac, Vascular, Pulmonary and Dietary . . . . . . . 899 51 Atherosclerotic Burden and Mortality . . . . . . . . . . . . . . . . . . . . . . . . . . . .901 J. Roquer . Angel Ois 52 Burden of Cardiovascular Diseases Among Aboriginal and Torres Strait Islander Peoples: Mortality, Hospitalization and Risk Factors . . . . .919 A. G. Thrift . S. L. Gall . A. D. Brown 53 Burden of Ischemic Heart Diseases in Serbia . . . . . . . . . . . . . . . . . . . . . .933 S. Sipetic-Grujicic . H. Vlajinac . J. Marinkovic . V. Bjegovic . I. Ratkov . J. Maksimovic 54 Burden of Cerebrovascular Diseases (Stroke) in Serbia . . . . . . . . . . . . . . .949 T. Pekmezovic . H. Vlajinac . S. Sipetic-Grujicic . N. Kocev . D. K. Tepavcevic . L. B. Bumbasirevic 55 DALYs and Public Health Programs for Stroke: Australian Perspectives . . .965 D. A. Cadilhac . M. L. Moodie . E. E. Lalor 56 Burden of Stroke: Indian Perspective . . . . . . . . . . . . . . . . . . . . . . . . . . . .991 P. M. Dalal . M. Bhattacharjee 57 Disability-Adjusted Life Years, Years of Life Lived with Disability, and Years of Life Lost in Stroke: Italian Perspectives . . . . . . . . . . . . . . . 1007 S. Mariotti 58 Burden of Ischemic Stroke and Benefits of Stroke Unit Care and Thrombolytic Therapy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1029 A. Meretoja . M. Kaste . T. Tatlisumak59 Economic Burden of Complications During Percutaneous Coronary Intervention . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1061 M. Dewan . K. M. Jacobson . C. S. Rihal 60 Features of Mediterranean Diet and Burden of Cardiovascular Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1073 D. B. Panagiotakos . C. Pitsavos . D. P. Mikhailidis 61 Obesity’s Final Toll: Influence on Mortality Rate, Attributable Deaths, Years of Life Lost and Population Life Expectancy . . . . . . . . . . .1085 K. R. Fontaine . S. W. Keith . J. A. Greenberg . S. J. Olshansky . D. B. Allison 62 Financial Impact of Obesity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1107 L. Barrios . D. B. Jones 63 Burden of Disease Attributable to Obesity and Overweight: Korean Focus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1119 Seok-Jun Yoon . Jae-Hyun Park 64 Economic Burden of the Components of the Metabolic Syndrome . . . . .1135 P. J. Marangos . L. J. Okamoto . J. J. Caro 65 Zinc Deficiency and DALYs in India: Impact Assessment and Economic Analyses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1151 A. J. Stein . M. Qaim . P. Nestel Part 2.5 Immune Disorders, Viral, Bacterial, Microbiological, Infectious and Parasitic Diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1171 66 The Impact of Infectious Diseases on the Development of Africa . . . . . .1173 A. Boutayeb 67 Measuring the Global Burden of Tuberculosis . . . . . . . . . . . . . . . . . . . .1189 I. Onozaki . N. Ishikawa . D. A. Enarson 68 Burden of Tuberculosis: Serbian Perspectives . . . . . . . . . . . . . . . . . . . . .1211 Z. Gledovic . H. Vlajinac . T. Pekmezovic . S. Grujicic-Sipetic . A. Grgurevic . D. Pesut 69 DALYs and Diarrhea . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1221 R. Oria . R. Pinkerton . AAM Lima . R. L. Guerrant 70 The Burden of Rotavirus Acute Gastroenteritis in Europe . . . . . . . . . . . .1233 J. Bilcke . P. Van Damme . P. Beutels71 The Economic Burden of Rotavirus Diarrhea: Taiwan Perspectives . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1243 Kow-Tong Chen 72 Disease Burden of Dengue Fever and Dengue Hemorrhagic Fever . . . . . 1263 J. A. Suaya . D. S. Shepard . Mark E. Beatty . J. Farrar 73 Cost-Effectiveness of a Dengue Vaccine in Southeast Asia and Panama: Preliminary Estimates . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1281 D. S. Shepard . J. A. Suaya 74 Burden of Sexually Transmitted Chlamydia trachomatis Infections . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1297 L. M. Niccolai . D. Berube 75 Disease Burden from Group A Neisseria meningitidis Meningitis in Hyperendemic Countries of the African Meningitis Belt . . . . . . . . . . . . . 1313 C. Suraratdecha . C. Levin . F. M. LaForce 76 DALYs in Chronic Hepatitis C : A Paneuropean Perspective . . . . . . . . . . 1323 U. Siebert . A. Conrads-Frank . R. Schwarzer . B. Lettmeier . G. Sroczynski . S. Zeuzem . N. Mu،§hlberger 77 Economics and Vaccines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1335 J. Bos . M. Postma 78 Economic Costs and Disability-Adjusted Life Years in Polio Eradication: A Long-Run Global Perspective . . . . . . . . . . . . . . . . . . . . . . 1353 M. M. Khan 79 Financial Burdens and Disability-Adjusted Life Years in Echinococcosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1373 P. R. Torgerson 80 Measuring Japanese Encephalitis (JE) Disease Burden in Asia . . . . . . . . 1391 W. Liu . D. Ding . J. D. Clemens . N. T. Yen . V. Porpit . Z..Y. Xu 81 Pandemic Influenza: Potential Contribution to Disease Burden . . . . . . . 1401 M. Nun.o 82 Prophylaxis of Healthcare Workers in an Influenza Pandemic . . . . . . . . 1419 S. M. Moghadas 83 The Burden of Human African Trypanosomiasis . . . . . . . . . . . . . . . . . . . 1433 A. Shaw . J. Robays . E. M. Fe`vre . P. Lutumba . M. Boelaert84 The Economic Burden of Malaria in Nigeria and Willingness to Pay . . . . 1443 A. Jimoh 85 Measurement of Adverse Health Burden Related to Sexual Behavior . . . 1459 S. H. Ebrahim . M. McKenna Volume 3 Part 2.6 Psychosocial, Social, Behavioural, Psychiatric, Neurological and Addictions . . . . . . . . . . . . . . . . . . 1471 86 Global Burden of Mental Health . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1473 M. Kastrup 87 Disease Burden and Disability-Adjusted Life Years Due to Schizophrenia and Psychotic Disorders . . . . . . . . . . . . . . . . . . . . . . . . .1493 A. Theodoridou . W. Ro¨ssler 88 The Societal Costs of Anxiety and Mood Disorders: An Epidemiological Perspective . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1509 R. C. Kessler . P. S. Wang . H.-U. Wittchen 89 Estimating the Disease Burden of Combat-Related Posttraumatic Stress Disorder in United States Veterans and Military Service Members . . . . .1527 M. C. Freed . R. K. Goldberg . K. L. Gore . C. C. Engel 90 Estimating the Disease Burden of Seasonal Affective Disorder . . . . . . . .1549 M. C. Freed . R. L. Osborn . K. J. Rohan 91 The Disease Burden of Suicide: Conceptual Challenges and Measurement Standards . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1569 C. A. Claassen . R. M. Bossarte . S. M. Stewart . E. Guzman . P. S. F. Yip 92 The Disease Burden Due to Epilepsy in Rural China . . . . . . . . . . . . . . . .1591 D. Ding . W. Z. Wang . Z. Hong 93 Alcohol Consumption and Burden of Disease: Germany and Switzerland . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1603 M. Roerecke . J. Rehm . J. Patra 94 Alcoholic Beverage Preference, Morbidity and Mortality . . . . . . . . . . . .1619 T. E. Strandberg 95 Burden of Disease Due to Alcohol and Alcohol Related Research . . . . . .1633 R. Rajendram . G. Lewison . V. R. Preedy 96 Years Life Lost Due to Smoking: A Korean Focus . . . . . . . . . . . . . . . . . .1649 S. Yoon97 The Health and Economic Consequences of Smoking and Smoking Cessation Interventions: The Dutch Perspective . . . . . . . . . . . . . . . . . . . 1661 M. P. M. H. Rutten-van Mo¨lken . T. Feenstra 98 Life Years Saved, Quality-Adjusted Life Years Saved and Cost-Effectiveness of a School-Based Tobacco Prevention Program . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1681 L. Y. Wang . C. Linda . R. Lowry . G. Tao Part 2.7 Sensory and Musculoskeletal . . . . . . . . . . . . . . . . . 1699 99 Burden of Disease and Years Lived with Disability Associated with Musculoskeletal Pain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1701 M. Suka . K. Yoshida 100 Financial Burdens and Disability-Adjusted Life Years in Loss of Vision Due to Trachoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1717 K. D. Frick 101 The Economic Burden of Rheumatoid Arthritis: Asia/Thailand Perspective . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1733 M. Osiri . A. Maetzel Part 3 Quality of Life Measures and Indices . . . . . . . . . . . . 1751 Part 3.1 General Aspects, Pathologies and Metabolic Disorders . . . . . . . . . . . . . . . . . . . . . . . . . . 1751 102 Quality of Life-Related Concepts: Theoretical and Practical Issues . . . . . 1753 A. A. J. Wismeijer . A. J. J. M. Vingerhoets . J. De Vries 103 Alternative Therapies and Quality of Life . . . . . . . . . . . . . . . . . . . . . . . . 1767 J. X. Zhang 104 Leisure-Time Physical Activity and Quality of Life . . . . . . . . . . . . . . . . . 1781 A. Vuillemin 105 Spa Therapy and Quality of Life . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1799 G. Blasche 106 Health-Related Quality of Life and Prioritization Strategies in Waiting Lists: Spanish Aspects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1811 M. Nu´nکez . E. Nu´nکez . J. M. Segur107 Hirsutism and Quality of Life . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1825 S. Davies 108 Oral Health-Related Quality of Life . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1839 U. Schu¨tte . M. Walter 109 Quality of Life Issues in Chronic Fatigue Syndrome . . . . . . . . . . . . . . . .1855 P. G. McKay . C. R. Martin 110 Hemoglobin Fluctuations and Correlation with Quality of Life and Fatigue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1867 G. Caocci . R. Baccoli . G. La Nasa 111 Anemia and Quality of Life: Association with Diagnosis and Treatment of Anemias . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1881 D. R. Thomas 112 Quality of Life in Hemophilia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1895 S. V. Mackensen . A Gringeri 113 Quality of Life in Amenorrhea and Oligomenorrhea . . . . . . . . . . . . . . . .1921 William W. K. To 114 Quality of Life Among Japanese Oral Contraceptive Users . . . . . . . . . . .1937 Y. Matsumoto . S. Yamabe . K. Ideta 115 Premenstrual Syndrome and Premenstrual Dysphoric Disorder: Issues of Quality of Life, Stress and Exercise . . . . . . . . . . . . . . . . . . . . .1951 M. Kathleen B. Lustyk . W. G. Gerrish 116 Quality of Life and Infertility . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1977 A. Montazeri 117 Speech Determines Quality of Life Following Total Laryngectomy: The Emperors New Voice? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1989 P. Farrand . R. Endacott 118 Health-Related Quality of Life of Living Kidney Donors . . . . . . . . . . . . .2003 Ja Hyeon Ku . Hyeon Hoe Kim 119 Quality of Life and Tryptophan Degradation . . . . . . . . . . . . . . . . . . . . .2027 D. Fuchs . K. Schroecksnadel . G. Neurauter . R. Bellmann-Weiler . M. Ledochowski . G. Weiss 120 L-Carnitine Supplementation on Quality of Life and Other Health Measures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2047 G. Mantovani . A. Maccio` . C. Madeddu . G. Gramignano121 Quality of Life Among Diabetic Subjects: Indian Perspectives . . . . . . . . 2071 K. Vijayakumar . R. T. Varghese 122 Healthy Lifestyle Habits and Health-Related Quality of Life in Diabetes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2095 C. Li . E. S. Ford 123 Quality of Life in Patients with Diabetic Foot Ulcers . . . . . . . . . . . . . . . . 2115 L. Ribu 124 Obstructive Sleep Apnea Hypopnea Syndrome and Quality of Life . . . . 2135 M. Hirshkowitz . A. Sharafkhaneh . H. Sharafkhaneh 125 Quality of Life and Pruritus . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2151 J. C. Szepietowski . A. Reich 126 Quality of Life and Costs in Atopic Dermatitis . . . . . . . . . . . . . . . . . . . . 2163 R. J. G. Arnold . R. K. Kuan 127 Quality of Life in Crohn’s Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2183 S. D. Wexner . J. C. Frattini 128 Impact of Self-Perceived Bothersomeness, Quality of Life and Overactive Bladder . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2195 Ja Hyeon Ku . Soo Woong Kim 129 Quality of Life in Men with Chronic Prostatitis/Chronic Pelvic Pain Syndrome . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2211 D. A. Tripp . J. C. Nickel 130 Quality of Life in Kidney Transplantation . . . . . . . . . . . . . . . . . . . . . . . . 2227 M. Veroux . D. Corona . V. B. Patel . P. Veroux 131 Quality of Life in Liver Cirrhosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2239 E. Kalaitzakis Volume 4 Part 3.2 Surgical . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2255 132 Quality of Life and Functional Outcome in Pediatric Patients Requiring Surgery: Italian Perspectives . . . . . . . . . . . . . . . . . . . . . . . . . 2257 M. Castagnetti 133 Breast Reduction Surgery and Quality of Life and Clinical Outcomes . . . 2271 A. Thoma . L. McKnight Table of Contents xvii134 Quality of Life and Postoperative Anesthesia in Gastrointestinal Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2287 R. Kennelly . A. M. Hogan . J. F. Boylan . D. C. Winter 135 Health-Related Quality of Life After Surgery for Crohn’s Disease . . . . . .2305 M. Scarpa . I. Angriman 136 Postoperative Quality of Life Assessment in the Over 80’s After Cardiac Surgery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2319 Christoph H. Huber 137 Quality of Life and Financial Measures in Surgical and Non-Surgical Treatments in Emphysema . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2335 J. D. Miller . F. Altaf 138 Quality of Life After Revascularization and Major Amputation for Lower Extremity Arterial Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2353 M. Deneuville 139 Quality of Life After Laser Surgery for Eye Disorders . . . . . . . . . . . . . . .2379 K. Pesudovs . D. B. Elliott Part 3.3 Early Life Stages and Aging . . . . . . . . . . . . . . . . . . . 2395 140 Intrauterine Growth Restriction and Later Quality of Life . . . . . . . . . . . .2397 D. Spence 141 Assessment of Quality of Life During Pregnancy and in the Postnatal Period . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2411 C. R. Martin . J. Jomeen 142 Generic Quality of Life Measures for Children and Adolescents . . . . . . .2423 K. J. Zullig . M. R. Matthews . R. Gilman . R. F. Valois . E. S. Huebner 143 Quality of Life in Children with Cerebral Palsy . . . . . . . . . . . . . . . . . . . .2453 A. Aran 144 Quality of Life Measures in Children with Cancer . . . . . . . . . . . . . . . . . .2469 C. H. Yeh . Y.-P. Kung . Y.-C. Chiang 145 Quality of Life in Healthy and Chronically Ill Icelandic Children: Agreement Between Child’s Self-Report and Parents’ Proxy-Report . . . . 2483 E. K. Svavarsdottir 146 Health-Related Quality of Life in Obese Children and Adolescents . . . . .2503 M. de Beer . R. J. B. J. Gemke147 Implementing Interventions to Enhance Quality of Life in Overweight Children and Adolescents . . . . . . . . . . . . . . . . . . . . . . . . . . 2517 J. Lamanna . N. Kelly . M. Stern . S. E. Mazzeo 148 Adolescent Quality of Life in Australia . . . . . . . . . . . . . . . . . . . . . . . . . . 2537 A. H. Lee . L. B. Meuleners . M. L. Fraser 149 Health-Related Quality of Life Among University Students . . . . . . . . . . . 2555 M. Vaez . M. Voss . L. Laflamme 150 The Quality of Life and the Impact of Interventions on the Health Outcomes of Looked After and Accommodated Young People . . . . . . . . 2579 D. Carroll . C. R. Martin 151 Quality of Life Measures During the Menopause . . . . . . . . . . . . . . . . . . 2593 G. D. Mishra . D. Kuh 152 Low Testosterone Level in Men and Quality of Life . . . . . . . . . . . . . . . . 2615 S. Horie 153 Measuring Quality of Life in Macular Degeneration . . . . . . . . . . . . . . . . 2633 J. Mitchell . C. Bradley 154 Quality of Life Measures in the Elderly and Later Life . . . . . . . . . . . . . . . 2649 S. Evans 155 Cochlear Implant Outcomes and Quality of Life in the Elderly . . . . . . . . 2667 S. R. Saeed . D. J. Mawman 156 Back Pain and Quality of Life in Elderly Women . . . . . . . . . . . . . . . . . . . 2675 K. Zhu . R. L. Prince 157 Measuring Quality of Life at the End of Life . . . . . . . . . . . . . . . . . . . . . . 2687 L. A. Roscoe . D. D. Schocken 158 Quality of Life Measures in the Elderly and the Role of Social Support in Elderly Chinese . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2705 L. Zhang . R. Hunter . C. Shao 159 Quality of Life in Elderly Dyspnea Patients . . . . . . . . . . . . . . . . . . . . . . . 2725 A. Hooshiaran . F. van der Horst . G. Wesseling . J. J. M. H. Strik . J. A. Knottnerus . A. Gorgels . A. Fastenau . M. van den Akker . J. W. M. Muris 160 Quality of Life and Age Urinary Incontinence Severity: Turkish Perspectives . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2745 T. M. Filiz . P. Topsever161 Quality of Life Measures in Elderly Patients with Chronic Obstructive Pulmonary Disease: Japanese Perspectives . . . . . . . . . . . . . . . . . . . . . .2759 K. Kida . T. Motegi . T. Ishii . K. Yamada Part 3.4 Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2779 162 Chemotherapy for Brain Metastasis and Quality of Life . . . . . . . . . . . . .2781 R. Addeo . G. Cimmino . S. D. Prete 163 Quality of Life Measures in Patients with Esophageal Cancer . . . . . . . . .2795 R. Parameswaran . J. C. Clifton . J. M. Blazeby 164 Quality of Life Measures in Head and Neck Cancer . . . . . . . . . . . . . . . . .2809 C. D. Llewellyn 165 Quality of Life in Breast Cancer Patients: An Overview of the Literature . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2829 A. Montazeri 166 Quality of Life with Localized Prostate Cancer: Japanese Perspectives . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2857 S. Namiki . L. Kwan . Y. Arai 167 Quality of Life in Men Undergoing Radical Prostatectomy for Prostate Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2875 M. Pearson . E. M. Wallen . R. S. Pruthi 168 Myeloproliferative Disorders and the Chronic Leukemias: Symptom Burden and Impact in Quality of Life . . . . . . . . . . . . . . . . . . . . . . . . . . .2887 R. A. Mesa . D. P. Steensma . T. Shanafelt 169 Quality of Life in Advanced Renal Cell Carcinoma: Effect of Treatment with Cytokine Therapy and Targeted Agents . . . . . . . . . . . .2905 S. Shah . K. Gondek 170 Quality of Life for Patients Receiving Cancer Chemotherapy: The Japanese Perspective . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2923 H. Uramoto . J. Tsukada 171 Quality of Life Measures in Caregivers of Patients with Cancer . . . . . . .2935 E. K. Grov . A. A. Dahl 172 Cancer: Influence of Nutrition on Quality of Life . . . . . . . . . . . . . . . . . . .2947 M. M. Mar‎´n Caro . C. PichardPart 3.5 Cardiovascular and Pulmonary . . . . . . . . . . . . . . . . 2965 173 Quality of Life, Drugs and Diet in Hypertensive Patients . . . . . . . . . . . . 2967 H. G. Kirpizidis 174 Measurement Issues in the Assessment of Quality of Life in Patients with Coronary Heart Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2987 D. R. Thompson . C. R. Martin 175 Influence of Age, Sex and Episode Recurrence on Quality of Life in Atrial Fibrillation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2999 M. R. Reynolds . A. S. Fein 176 Quality of Life Measures in Acute Coronary Syndromes: The Evaluation of Predictors in this Field of Research . . . . . . . . . . . . . . 3015 R. Coelho . J. Prata 177 Home Mechanical Ventilation and Quality of Life Measures . . . . . . . . . . 3035 J. L. Lo´pez-Campos . W. Windisch . I. Failde 178 Quality of Life in Children with Asthma . . . . . . . . . . . . . . . . . . . . . . . . . 3055 M. L. Marsac 179 Efficacy of Environmental Interventions on Asthma-Related Quality of Life . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3073 J. E. Clougherty 180 Chronic Obstructive Pulmonary Disease, Lung Function and Quality of Life in Adult Chinese . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3085 G. Xie . A. Paice . Y. Wu Part 3.6 Dietary and Nutritional . . . . . . . . . . . . . . . . . . . . . . . 3097 181 Health-Related Quality of Life in Eating Disorders . . . . . . . . . . . . . . . . . 3099 C. Las Hayas . J. A ´ . Padierna . P. Munکoz 182 Weight-Related Stigmatization: Effects on the Quality of Life of Obese Adolescents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3137 N. R. Kelly . R. W. Gow . M. Stern . S. E. Mazzeo 183 Malnutrition in Chronic Kidney Disease and Relationship to Quality of Life . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3159 B. Kalender184 Nutrition and Quality of Life in Hemodialysis – the Impact of Nutritional Status and Quality of Life on Morbidity and Mortality in Hemodialysis Patients . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3171 B. Feldt-Rasmussen . T. A. Ikizler . K. Kalantar-Zadeh . J. D. Kopple 185 Nutritional Wasting in Cancer and Quality of Life: The Value of Early Individualized Nutritional Counseling . . . . . . . . . . . . . . . . . . . . . . . . . . .3189 P. Ravasco . I. M. Grillo . M. Camilo Part 3.7 Immune Disorders, Viral, Bacterial, Microbiological, Infectious and Parasitic Diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3205 186 Quality of Life Measures in HIV Low Income Women: How to Use Quality of Life to Design, Implement and Evaluate Programs . . . . . . . . .3207 K. A. McDon