Principles of clinical cancer genetics : a handbook from the Massachusetts General Hospital
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Daniel C Chung; Daniel A Haber; Massachusetts General Hospital.
- ناشر : New York : Springer
- چاپ و سال / کشور: 2010
- شابک / ISBN : 9780387938448
Description
Basic principles of cancer genetics Principles of Cancer Genetic Counseling and Genetic Testing Genetics of Hereditary Breast Cancer Surgical management of Hereditary Breast and Ovarian Cancer Hereditary colon cancer: Colonic Polyposis Syndromes Hereditary colon cancer: Lynch Syndrome Hereditary Pancreatic Cancer Hereditary Diffuse Gastric Cancer Familial Renal Cell Cancers and Pheochromocytomas Familial Atypical Mole Melanoma (FAMM) Syndrome Multiple Endocrine Neoplasia Pediatric malignancies: Retinoblastoma and Wilms' tumor Neurofibromatosis and Schwannomatosis The Hap Map project and low penetrance cancer susceptibility alleles Somatic genetic alterations and implications for targeted therapies in cancer (GIST, CML, Lung cancer)
This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed.
