Cytogenetics, FISH and molecular testing in hematologic malignancies
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Wojciech Gorczyca
- ناشر : London : Informa Healthcare
- چاپ و سال / کشور: 2008
- شابک / ISBN : 9780415420099
Description
Chapter 1. Introduction 1 Karyotype 2 Nomenclature 3 Conventional cytogenetics 4 Fluorescence in situ hybridization 9 Molecular pathology 19 Immunophenotyping by flow cytometry 23 Immunohistochemistry 26 Chapter 2. Applications of cytogenetics, FISH, and PCR in diagnosis, 31 prognosis, and disease monitoring Most common chromosomal/molecular abnormalities 31 Application of chromosomal and molecular markers in diagnosis 97 Application of chromosomal and molecular markers in prognostification 106 Application of chromosomal and molecular markers in disease monitoring 108 Chapter 3. Hematologic malignancies: correlation between morphology, phenotype, 115 and chromosomal/genetic markers B-cell lymphoproliferations 115 Peripheral (mature) T-cell lymphoproliferative disorders 166 Hodgkin lymphoma 182 Acute myeloid leukemia 183 Precursor lymphoblastic lymphoma/leukemia (acute lymphoblastic leukemia) 198 Chronic myeloproliferative disorders 205 Mastocytosis 224 vi CONTENTS Myeloproliferative/myelodysplastic diseases 225 Myelodysplastic syndromes 226 Abbreviations/terminology 233 References 235
