Enzybiotics : antibiotic enzymes as drugs and therapeutics
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Tomás González Villa; Patricia Veiga-Crespo
- ناشر : Hoboken, N.J. : John Wiley & Sons
- چاپ و سال / کشور: 2010
- شابک / ISBN : 9780470376553
Description
Enzybiotics and their potential applications in medicine / Jan Borysowski and Andrzej Górski -- Advantages and disadvantages in the use of antibiotics or phages as therapeutical agents / Patricia Veiga-Crespo and Tomas G. Villa -- Enzybiotics as selective killers of target bacteria / Juan C. Alonso and Marcelo E. Tolmasky -- Phylogeny of enzybiotics / Patricia Veiga-Crespo and Tomas G. Villa -- Bacteriophage lysins : the ultimate enzybiotic / Vincent A. Fischetti -- Bacteriophages holins and their membrane-disrupting activity / María Gasset -- Anti-staphylococcal lytic enzymes / Jan Borysowski and Andrzej Górski -- Membrane-targeted enzybiotics / María Gasset -- Design of phage cocktails for therapy from a host range point of view / Lawrence D. Goodridge -- Identifying phage lytic enzymes : past, present, and future / Jonathan E. Schmitz, Raymond Schuch, and Vincent A. Fischetti -- Use of genetically modified phages to deliver suicidal genes to target bacteria / Lawrence D. Goodridge.
Enzybiotics, by using enzymes to fight bacteria, offer a novel and promising new way to combat infectious diseases. This book presents the state-of-the-art and therapeutic potential of enzybiotics, with a stress on therapeutic applications. The coverage offers a unique combination of medicinal chemistry, microbiology, genetics, and biochemistry.
