Drug transporters : molecular characterization and role in drug disposition
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Guofeng You; Marilyn Emily Morris
- ناشر : Hoboken, N.J. : Wiley-Interscience
- چاپ و سال / کشور: 2007
- شابک / ISBN : 9780471784913
Description
Overview of drug transporter families / Guofeng You and Marilyn E. Morris -- Organic cation transporters / Thomas J. Urban and Kathleen M. Giacomini -- Organic cation/carnitine transporters / Ijaz A. Qureshi ... [et al.] -- Organic anion transporters / Megha Nagle ... [et al.] -- Organic anion-transporting polypeptides / Rommel G. Tirona and Richard B. Kim -- Mammalian oligopeptide transporters / Stephen M. Carl ... [et al.] -- Monocarboxylate transporters / Justin A. Spanier and Lester R. Drewes -- Nucleoside transporters : CNTs and ENTs / Li Xia, Mingyan Zhou, and Joanne Wang -- Bile acid transporters / Jyrki J. Eloranta and Gerd A. Kullak-Ublick -- Multidrug resistance protein : P-glycoprotein / Frances J. Sharom -- Multidrug resistance proteins of the ABCC subfamily / Anne T. Nies, Maria Rius, and Dietrich Keppler -- Breast cancer resistance protein / Robert W. Robey ... [et al.] -- Drug transport in the liver / Pieter Annaert ... [et al.] -- Drug transport in the brain / Patrick T. Ronaldson, Karlo Babakhanian, and Reina Bendayan. Drug transport in the kidney / Naohiko Anzai and Hitoshi Endou -- Drug transporters in the intestine / Yaming Su and Patrick J. Sinko -- Regulation of drug transporter activity / Mei Hong and Guofeng You -- Experimental approaches to the study of drug transporters / Yoshiyuki Kubo, Yukio Kato, and Akira Tsuji -- In vitro-in vivo scale-up of drug transport activities / Kazuya Maeda and Yuichi Sugiyama -- Age- and gender-related differences in xenobiotic transporter expression / Curtis D. Klaassen and Xingguo Cheng -- Polymorphisms of drug transporters and clinical relevance / Leslie W. Chinn, Jason M. Gow, and Deanna L. Kroetz -- Diet/nutrient interactions with drug transporters / Xiaodong Wang and Marilyn E. Morris -- Interplay of drug transporters and enzymes on hepatic drug processing / K. Sandy Pang, Huadong Sun, and Shanjun Liu -- Clinical relevance : drug-drug interactions, pharmacokinetics, pharmacodynamics, and toxicity / Serena Marchetti ... [et al.].
This title fills a gap in highlighting the advances in the identification, principles and background of drug transporters. Offering a timely overview of the relevant drug transporters, this adaptable text discusses specific types of drug transporters for both beginning and experienced scientists and researchers.
