Cancer pain : assessment and management

Contents Contributors vii Preface xi Color plates follow page 420 SECTION I MECHANISMS AND EPIDEMIOLOGY 1 Nociception: basic principles 3 Rie Suzuki, Shafaq Sikandar, and Anthony H. Dickenson 2 Pathophysiology of malignant bone pain 23 Juan Miguel Jimenez-Andrade, Monica Herrera, and Patrick Mantyh SECTION II EPIDEMIOLOGY AND SYNDROMES 3 Cancer pain epidemiology 37 Irene J. Higginson and Fliss Murtagh 4 Cancer pain syndromes 53 Mervyn Koh and Russell K. Portenoy SECTION III ASSESSMENT 5 The assessment of cancer pain: measurement strategy 89 Karen O. Anderson 6 Multidimensional assessment: pain and palliative care 105 Norma O’Leary, Carol Stone, and Peter G. Lawlor 7 Evaluating pain for children with cancer 130 Patricia A. McGrath and Eric J. Crawford 8 Pain syndromes in cancer survivors 145 Rosemary C. Polomano, Michael Ashburn, and John T. Farrar SECTION IV PHARMACOLOGICAL TREATMENT 9 Pharmacology of analgesia: basic principles 167 Charles E. Inturrisi 10 Pharmacogenetic considerations in the treatment of cancer pain 180 P°al Klepstad 11 Pharmacology of opioid analgesia: clinical principles 195 Carla Ida Ripamonti and Claudia Bareggi 12 Opioid side effects and management 230 Maxine de la Cruz and Eduardo D. Bruera 13 Antipyretic analgesics 255 Burkhard Hinz and Kay Brune 14 Adjuvant analgesic drugs 272 Russell K. Portenoy and Mervyn Koh 15 Neuraxial analgesia 287 Lewis C. Holford and Michael Cousins SECTION V OTHER INTERVENTIONAL STRATEGIES 16 Neural blockade for cancer pain 315 Rebecca Chan and Oscar de Leon-Casasola 17 Neurosurgical treatment of cancer pain 329 Robert W. Hurley and Fred A. Lenz SECTION VI REHABILITATION AND PSYCHOLOGICAL INTERVENTIONS 18 Psychological interventions for cancer pain 343 Francis J. Keefe, Amy P. Abernethy, Jane L. Wheeler, and Tamara J. Somers v vi contents 19 Rehabilitation medicine interventions 354 Jack B. Fu, Ki Y. Shin, and Theresa A. Gillis SECTION VII THE ROLE OF ANTINEOPLASTIC THERAPIES IN PAIN CONTROL 20 Palliative radiotherapy 379 Alysa Fairchild and Edward Chow 21 Palliative systemic antineoplastic therapy 399 Sunil M. Patel and Michael J. Fisch SECTION VIII PAIN IN SPECIAL POPULATIONS 22 Cancer pain management in the chemically dependent patient 423 Steven D. Passik, Lara K. Dhingra, and Kenneth L. Kirsh 23 Cancer pain in children 433 Richard Hain 24 Managing cancer pain in the elderly 444 Marvin Omar Delgado-Guay and David Wollner SECTION IX DIFFICULT PAIN PROBLEMS 25 Cancer pain and depression 457 William S. Breitbart, Wendy G. Lichtenthal, Hayley Pessin, and Gloria C. Lee 26 Neuropathic pain 478 Ricardo A. Cruciani, E. Alessandra Strada, and Helena Knotkova 27 Breakthrough pain 506 Sebastiano Mercadante 28 Bone pain 515 Badi El Osta and Eduardo D. Bruera SECTION X SYSTEMS OF CARE 29 Integrating cancer pain management into hospice practice and institution-based palliative care programs 535 Sandra P. Gomez and Paul W. Walker 30 Pain in medical illness: ethical and legal foundations 553 Pauline Lesage and Russell K. Portenoy 31 Understanding clinical trials in pain research 568 John T. Farrar and Scott D. Halpern 32 Legal and regulatory aspects of opioid treatment: the United States experience 583 June L. Dahl 33 Role of family caregivers in cancer pain management 597 Myra Glajchen 34 Cancer pain and palliative care in the developing world 608 Roberto Wenk, Daniela Mosoiu, and M. R. Rajagopal Index