Transgenic mouse : methods and protocols
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Marten H Hofker; Jan van Deursen
- ناشر : Totowa, NJ : Humana Press
- چاپ و سال / کشور: 2003
- شابک / ISBN : 9780585442174
Description
Introduction : The Use of Transgenic Mice in Biomedical Research / Marten H. Hofker -- Genetic Modification of the Mouse : General Technology; Pronuclear and Blastocyst Injection / J. Willem Voncken -- In Vitro Fertilization/Cryopreservation / Susan Marschall, Martin Hrabe de Angelis -- Transgene Design / J. Willem Voncken -- Generating Conditional Mouse Mutants via Tetracycline-Controlled Gene Expression / Kal Schonig, Hermann Bujard -- Manipulating Large Insert Clones for Transgenesis / Sally P. A. McCormick ... [et al.] -- Reporter Molecules in Genetically Engineered Mice / Thomas L. Saunders -- Gene Targeting in Mouse Embryonic Stem Cells / Jan van Deursen -- Conditional Knockout Mice / Ralf Kuhn, Frieder Schwenk -- Knockin Approaches / Anton J. M. Roebroek, Xiaosheng Wu, Richard J. Bram -- Aggregation of Embryos and Embryonic Stem Cells / Ronald Maatman ... [et al.] -- Andenovirus-Mediated Gene Transfer / Ko Willems van Dijk ... [et al.] -- Random ENU Mutagenesis / Dian Soewarto, Veronique Blanquet, Martin Hrabe de Angelis -- Autopsy and Histologic Analysis of the Transgenic Mouse / Marion J. J. Gijbels, Menno P. J. de Winther -- Bone Marrow Transplantations to Study Gene Function in Hematopoietic Cells / Menno P. J. de Winther, Peter Heeringa -- Quantification of Atherosclerosis in Mice / Alan Daugherty, Stewart C. Whitman -- Genetically Modified Mice in Cancer Research / David A. Largaespada -- Neuropathobiology in Transgenic Mice: The Case of Alzheimer's Disease / Jo Van Dorpe ... [et al.].
