Mechanisms and concepts in toxicology
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : W Norman Aldridge
- ناشر : London, UK ; Bristol, PA, USA : Taylor & Francis
- چاپ و سال / کشور: 1996
- شابک / ISBN : 9780748404131
Description
1. Scope of Toxicology -- 2. Stages in the Induction of Toxicity -- 3. Kinetics and End-points -- 4. Acute and Chronic Intoxication -- 5. Delivery of Intoxicant: Decrease in delivery to the target -- 6. Delivery of Intoxicant: Bioactivation and increase in delivery to the target -- 7. Initiating Reactions with Targets -- 8. Biological Consequences of Initiating Reactions with Targets -- 9. Exposure, Dose and Chemical Structure, Response and Activity, and Thresholds -- 10. Selective Toxicity, Animal Experimentation and In Vitro Methods -- 11. Biomonitoring -- 12. Epidemiology -- 13. Environmental and Ecotoxicology -- 14. Reflections, Research and Risk.
An erroneous perception of risk from exposure to chemicals is that it is higher than other risks to which we are subject; it is also believed that exposure to synthetic chemicals is more hazardous than exposure to natural toxins that are present in air, water, plants and animals. This book, by clarifying the principles that apply to all chemicals and all organisms, including humans, explains why some chemicals are
