Laboratory design guide : for clients, architects, and their design team : the laboratory design process from start to finish: 3rd

List of figures xiii List of colour plates xv Acknowledgements xvii Introduction xix Summary of recommendations xxi Chapter 1 – Design brief 1 1.1 Initiating the brief 2 1.2 Generic laboratories 4 1.3 Type and function of the laboratory 4 1.4 Staff 7 1.5 Hazards 7 1.6 Work space, benches and services 9 1.7 Storage 9 1.8 Equipment 11 1.9 Work environment 12 1.10 Staff facilities 12 1.11 Meeting rooms 13 1.12 Car parking 14 1.13 Visitors 14 1.14 Security 14 1.15 Case studies 14 Chapter 2 – Design methodology 15 2.1 Project team 16 2.2 Project meetings 16 2.3 Project programme and budget 17 2.4 Returning the brief 17 viii Contents 2.5 Design synthesis 19 2.6 Design development 19 2.7 Contract documentation 19 2.8 Construction management 22 Chapter 3 – Site and buildings 23 3.1 Location 24 3.2 Site planning 25 3.3 Building design 25 3.4 Interior design 31 3.5 Special laboratories 37 3.6 External bulk storage 37 3.7 Teaching laboratories and the virtual experiment 37 Chapter 4 – Laboratory furniture and services 39 4.1 Workbenches 40 4.2 Storage cupboards and drawers 45 4.3 Non-joinery items of furniture 45 4.4 Glass wash facilities 47 4.5 Laboratory services 47 4.6 Recent technology 49 Chapter 5 – Special cabinets and benches 51 5.1 Fume cupboards 52 5.2 Local exhaust ventilation 55 5.3 Biological safety cabinets 56 5.4 Laminar flow cabinets 56 5.5 Down-draught benches 56 5.6 Flammable liquids cabinets 56 5.7 Decanting benches 58 5.8 Anti-vibration benches 58 5.9 Equipment/instrumentation benches 58 5.10 Workbenches for disabled staff 59 Chapter 6 – Laboratory computers, instrumentation and equipment 61 6.1 Computers 62 6.2 Instrumentation for analysis and testing 63 6.3 Centrifuges 63 6.4 Ovens and autoclaves 64 6.5 Incubators 64 Contents ix 6.6 Refrigerators and cool rooms 64 6.7 Access for large equipment 65 Chapter 7 – On completion 67 7.1 Commissioning equipment 68 7.2 Security 68 7.3 Emergency procedures 69 7.4 Services controls and emergencies 69 7.5 Building manual 69 7.6 As-built drawings 69 7.7 Joint final inspections 70 7.8 Publication 70 Chapter 8 – Maintenance 71 8.1 Bench tops 72 8.2 Flooring 72 8.3 Filters 73 8.4 Waste disposal 73 8.5 Safety stations 73 8.6 Laboratory services and equipment 74 8.7 Laboratory audits 74 Chapter 9 – Environmental design: Internal courtyards as an element of ESD 75 Matthew Jessup, BE (Hons), Senior Environmental Analyst and Su-fern Tan (BE, BA, DipEngPrac), Environmental Analyst, Advanced Environmental Concepts 9.1 Introduction 76 9.2 Design elements 77 9.3 The benefits of internal courtyards 78 9.4 A simple concept 78 9.5 Conclusion 79 Chapter 10 – Occupational health and safety 81 Caroline Langley BSc M Safety Sc Grad Dipl Occup Hygiene MSIA, Director, Injury Prevention & Management, Hobart,Tasmania 10.1 Introduction 82 10.2 Design Hazard Review 82 10.3 Hierarchy of control 84 10.4 Sources of information in Australia 87 10.5 Conclusion 88 x Contents Chapter 11 – Hydraulic services 89 Livio Chiarot, Dip Tech MIE Aust AHSCA APPA, Director of Acor Consultants, Engineers, Managers, Infrastructure Planners 11.1 General 90 11.2 Sanitary drainage and plumbing 90 11.3 Water systems 91 11.4 System features 91 11.5 Materials selection 94 11.6 Waste disposal 95 Chapter 12 – Mechanical services 97 Robert Lord, BE Mechanical (Hons) Grad Dip Management RPEQ, Senior Engineer Lincolne Scott 12.1 General 98 12.2 Decoupled design approach 100 12.3 Integration with other consultants 102 12.4 Air quality systems 103 12.5 Thermal control systems 107 12.6 Acoustic considerations 110 12.7 Energy considerations 110 12.8 Future proofing considerations 112 Chapter 13 – Electrical services 113 James McPherson, BE (Elec) MIE Aust, Manager, Building and Industrial Services, GHD Pty Ltd., Newcastle 13.1 Introduction 114 13.2 Relevant Australian codes and standards 115 13.3 Power supply and reticulation 115 13.4 Bench electrical services 117 13.5 Electrical safety 119 13.6 Hazardous zones 120 13.7 General lighting 121 Chapter 14 – Project cost control 125 Ken McGowan, FRICS FAIQS, Senior Partner of the WT Partnership, Quantity Surveyors Chapter 15 – Post-occupancy evaluation 133 Doug Pottrell, Manager, School of Molecular and Biomedical Science, University of Adelaide 15.1 Introduction 134 15.2 Brief 134 Contents xi 15.3 Layout 134 15.4 Flexibility 135 15.5 Laboratories 135 15.6 Air conditioning 135 15.7 Features 136 15.8 Security 136 15.9 Space in demand 136 15.10 Room for the future 136 15.11 Summary 136 Case studies 139 This is a selection of laboratory buildings and projects including university teaching and research, product quality assurance, research and development, testing laboratories, pathology services and medical research. 1 Biology Teaching and Research Building, University of Wollongong, NSW 143 2 Biological Sciences & Biomedical Engineering, University of New South Wales, Sydney, NSW 150 3 Children’s Medical Research Foundation,Westmead, NSW 154 4 Centenary Institute of Cancer Medicine & Cell Biology, Sydney, NSW 158 5 SmithKline Beecham International Laboratories, Consumer Healthcare, Ermington, NSW 160 6 Life Sciences Building, Ciba Pharmaceuticals Division, Summit, New Jersey, USA 162 7 Pacific Power Research Laboratories, University of Newcastle, NSW 167 8 CSIRO McMasters Laboratories, Prospect, NSW 172 9 ANSTO Radiopharmaceutical Laboratory, Lucas Heights, NSW 175 10 Garvan Institute of Medical Research, Sydney, NSW 178 11 ACTEW Corporation Laboratories, Fyshwick,ACT 181 12 Camelia Botnar Laboratories, Great Ormond Street Hospital, London 188 13 Institute of Medical Science,The University of Aberdeen, Scotland 191 14 Heritage Medical Research Building, University of Alberta, Canada 195 15 Balgownie Technology Centre, Aberdeen Science Park, Scotland 200 16 St Michael’s Science Building, University of Portsmouth, UK 204 17 Eli Lilly and Co. Product Development Research Laboratories, Indianapolis, USA 207 18 Australian Geological Survey Organisation, Canberra,ACT 211 19 Sir Alexander Fleming Building, Imperial College, London, UK 216 20 Trinity College Dublin, East End Development, Dublin, Ireland 220 21 Strathclyde Institute for Biomedical Sciences, Glasgow, Scotland 224 22 Hunter Water Australia, Newcastle, NSW 228 23 Analytical Research Laboratories, Napier, New Zealand 232 24 Biomedical Building,ATP, Sydney, NSW 235 25 New Science Building, University of Adelaide, SA 241 26 Center for Clinical Sciences Research, Stanford University, USA 245 27 Laboratory Design Competition at the University of Newcastle, NSW 248 28 Laboratory Design Competition at the University of Queensland, Australia 253 29 Institute of Medical Sciences: Phase 2, University of Aberdeen, Scotland 257 30 CSIRO Molecular Science and Food Science Australia, North Ryde, NSW 260 31 Liverpool Biosciences Centre, University of Liverpool, UK 264 32 Kadoorie Biological Sciences Building, University of Hong Kong 269 33 Institute of Laboratory Medicine, St Vincent’s Hospital Campus, Sydney 279 34 Life Sciences Building, University of Newcastle, NSW 283 35 Hunter Area Pathology Services (HAPS), John Hunter Hospital Campus, Newcastle, NSW 288 36 Mine Safety Technical Facility, NSW Department of Mineral Resources, Maitland, NSW 292 37 Dow Corning Research, Macquarie Technology Park, Sydney 294 38 National Marine Science Centre, Coffs Harbour, NSW 296 39 CSIRO Energy Centre, Steel River, Newcastle, NSW 300 40 Boehringer Biological Research Institute, Biberach, Germany 308 41 James H Clark Center, Stanford University, California, USA 313 42 Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland 319 43 30 The Bond, Bovis Lend Lease Head Office, Sydney, Australia 326 Appendix A – Notes on laboratory construction 329 Appendix B – Australian Laboratory Standards 333 Index 341