Biomarkers for antioxidant defense and oxidative damage : principles and practical applications
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Giancarlo Aldini; et al
- ناشر : Ames, Iowa : Wiley-Blackwell
- چاپ و سال / کشور: 2010
- شابک / ISBN : 9780813815350
Description
Antioxidant activity and oxidative stress : an overview / Kyung-Jin Yeum, Robert M. Russell, and Giancarlo Aldini -- Enzymatic antioxidant defenses / Sayuri Miyamoto, Hirofumi Arai, and Junji Terao -- Antioxidant as biomarkers of oxidative stress / Ikuyo Ichi and Shosuke Kojo -- LDL oxidation as a biomarker of antioxidant status / Mohsen Meydani, EunHee Kong, and Ashley Knight -- The isoprotanes : accurate markers and potent mediators of oxidant injury in vivo / Joshua D. Brooks ... [et al.] -- Hydroxyoctadecadienoic acid (HODE) as a marker of linoleic acid oxidation / Yasukazu Yoshida and Etsuo Niki -- Oxysterols : potential biomarkers of oxidative stress / Luigi Iuliano and Ulf Diczfalusy -- Lipid peroxidatin originating unsaturated aldehydes and their metabolites as biomarkers / Françoise Guéraud -- Oxidation modification of proteins : an overview / Paul J. Thornalley and Naila Rabbani -- Immunochemical detection of lipid peroxidation-specific epitopes / Koji Uchida -- Mass spectrometric strategies for identification and characterization of cabonylated peptides and proteins / Marina Carini and Marcia Orioli -- Nitrotyrosine : quantitative analysis, mapping in proteins, and biological significance / José Souza ... [et al.] -- Ubiquitin conjugates : a sensitive marker of oxidative stress / Fu Shang and Allen Taylor -- Covalent modifications of albumin cys34 as a biomarker of mild oxidative stress / Giancarlo Aldini, Kyung-Jin Yeum, and Giulio Vistoli -- Protein S-glutathionilation and S-cysteinilation / Graziano Colombo ... [et al.] -- DNA oxidation, antioxidant effects, and DNA repair measured with the comet assay / Mária Duinšká and Andrew R. Collins -- Hydroxylated nucleotides : measurement and utility as biomarkers of DNA damage, oxidative stress, and antioxidant efficacy / Phyllis E. Bowen -- Exocylic DNA adducts as biomarkers of antioxidant defense and oxidative stress / Roger W.L. Godschalk
Discovering sensitive and specific biomarkers for systemic oxidative damage is essential to better understand the role of oxidative stress in human disease. Once these roles are more clearly understood we are able to identify novel drug and nutraceutical targets
