Global burden of disease and risk factors

Foreword / Samuel H. Preston -- Preface -- Editors -- Advisory committee to the editors -- Contributors -- Disease control priorities project partners -- Acknowledgments -- Abbreviations and acronyms -- ch. 1. Measuring the global burden of disease and risk factors, 1990-2001 / Alan D. Lopez, Colin D. Mathers, Majid Ezzati, Dean T. Jamison, and Christopher J.L. Murray -- History of burden of disease studies -- Applications of burden of disease analysis -- Improving the comparative quantification of diseases, injuries, and risk factors : the 2001 GBD study -- Major findings of the 2001 GBD study -- Conclusions -- References -- pt. 1. Global burden of disease and risk factors -- ch. 2. Demographic and epidemiological characteristics of major regions, 1990-2001 / Alan D. Lopez, Stephen Begg, and Ed Bos -- Regional demographic characteristics -- Changes in mortality, 1990-2001 -- Trends in causes of child death, 1990-2001 -- Discussion -- Conclusions -- Annex 2A : key demographic indicators, by country/territory, 1990 and 2001 -- Acknowledgments -- Notes -- References. ch. 3. The burden of disease and mortality by condition : data, methods, and results for 2001 / Colin D. Mathers, Alan D. Lopez, and Christopher J.L. Murray -- Quantifying the global burden of disease -- Estimating deaths by cause : methods and data -- Global and regional mortality in 2001 -- Estimating incidence, prevalence, and YLD : methods and data -- Burden of disability and poor health in 2001 -- Global burden of disease in 2001 -- Discussion and conclusions -- Annex 3A : definitions, mortality data sources, and disability weights -- Annex 3B: deaths by cause, sex, age, and region, 2001 -- Annex 3C: DALYs (3,0) by cause, sex, age, and region, 2001 -- Acknowledgments -- References -- ch. 4. Comparative quantification of mortality and burden of disease attributable to selected risk factors / Majid Ezzati, Stephen Vander Hoorn, Alan D. Lopez, Goodarz Danaei, Anthony Rodgers, Colin D. Mathers, and Christopher J.L. Murray -- Burden of disease attributable to risk factors -- Risk factor selection -- Burden of disease attributable to individual risk factors -- Joint effects of multiple risk factors -- Burden of disease attributable to multiple risk factors -- Directions for future research -- Discussion -- Annex 4A: population attributable fractions, attributable deaths, years of life lost because of premature mortality (YLL), and disability-adjusted life years (DALYs) by risk factor, disease outcome, age, sex, and region -- References. pt. 2. Sensitivity analyses -- ch. 5. Sensitivity and uncertainty analyses for burden of disease and risk factor estimates / Colin D. Mathers, Joshua A. Salomon, Majid Ezzati, Stephen Begg, Stephen Vander Hoorn, and Alan D. Lopez -- Discounting and age weighting in the DALY measure -- Sensitivity of burden of disease and injury results to variations in key parameter values -- Sensitivity of risk factor estimates to variations in key parameter values -- Uncertainty analysis of the global burden of disease estimates -- Uncertainty estimates for all-cause mortality and life expectancies -- Uncertainty estimates for regional mortality by cause -- Uncertainty in disability weights -- Uncertainty arising from epidemiological estimates -- Uncertainty in the disease burden attributable to risk factors -- Discussion -- Conclusions -- Acknowledgments -- References. ch. 6. Incorporating deaths near the time of birth into estimates of the global burden of disease / Dean T. Jamison, Sonbol A. Shahid-Salles, Julian Jamison, Joy E. Lawn, and Jelka Zupan -- Stillbirths and neonatal mortality in the context of the global burden of disease -- The burden of disease resulting from events near the time of birth -- Conclusions -- Annex 6A : flexible functional forms for the acquisition of life potential -- Annex 6B : flexible functional forms for the acquisition of life potential -- Annex 6C : causes of neonatal mortality : comparison of numbers from the global burden of disease with those from the Child Health Epidemiology Reference Group -- Acknowledgments -- References -- Glossary -- Index.