Nutrients and cell signaling

Series Introduction........................................................................... vii Preface................................................................................................ xi Contributors..................................................................................... xiii I. NUCLEAR RECEPTORS, TRANSCRIPTION FACTORS, AND SIGNALING CASCADES ........................ 1 1. NFκB-Dependent Signaling Pathways .................................... 3 Xiaoxia Li 2. Nuclear Receptors and Dietary Ligands ............................... 35 Miriam N. Jacobs 3. Retinoid Signaling ................................................................... 91 Dianne Robert Soprano, Pu Qin, and Kenneth J. Soprano 4. Regulation of Cytokines and Immune Function by 1,25-Dihydroxyvitamin D3 and Its Analogs ................... 127 Evelyne van Etten, Annapaula Giulietti, Conny Gysemans, Annemieke Verstuyf, Lut Overbergh, and Chantal Mathieu 5. Vitamin D-Regulated Pathways: Impact on Cell Proliferation, Differentiation, and Apoptosis ...................... 165 JoEllen Welsh 6. Effects of Nutrient Deprivation on the Expression of Growth-Arrest Genes ........................................................ 193 William D. Rees xxii Contents 7. Mechanisms for Dietary Regulation of Nitric Oxide Synthesis in Mammals.......................................................... 225 Nick E. Flynn, Cynthia J. Meininger, Tony E. Haynes, Wenjuan Shi, and Guoyao Wu 8. The Roles of Thioredoxin Reductases in Cell Signaling .... 253 Dan Su and Vadim N. Gladyshev 9. Roles for Biotinylation of Histones in Chromatin Structure ................................................................................ 277 Gabriela Camporeale, Nagarama Kothapalli, Gautam Sarath, and Janos Zempleni II. AMINO ACIDS, LIPIDS, AND GLYCATION................ 297 10. Nutrient Signaling to Muscle and Adipose Tissue by Leucine.............................................................................. 299 Thomas C. Vary and Christopher J. Lynch 11. Anabolic Effects of Amino Acids and Insulin in the Liver ............................................................................ 329 Luc Bertrand and Louis Hue 12. Amino Acid-Sensing mTOR Signaling................................. 353 Ebru Erbay, Jae Eun Kim, and Jie Chen 13. Alterations in Glutamate Trafficking and Signal Transduction Pathways in Hyperammonemia.................... 381 Helen Chan and Roger F. Butterworth 14. The Influence of Lipids on Nuclear Protein Import, Cell Growth, and Gene Expression...................................... 411 Randolph S. Faustino, Melanie N. Landry, Nicole T. Gavel, Michael P. Czubryt, and Grant N. Pierce 15. Isoprenoid Regulation of the Expression of Ras and Ras- Related Proteins .................................................................... 439 Sarah A. Holstein and Raymond J. Hohl Contents xxiii 16. Amino Acid Signaling and the Control of Autophagy ........ 461 Alfred J. Meijer, Peter F. Dubbelhuis, Edward F.C. Blommaart, and Patrice Codogno 17. A Nutrient-Sensing Hexosamine Signaling Pathway......... 491 Dona C. Love and John A. Hanover III. INSULIN RELEASE, SIGNALING, AND INSULIN RESISTANCE ................................................... 531 18. Pancreatic β-Cell, a Unique Fuel Sensor............................. 533 Mitsuhisa Komatsu 19. Metabolic Actions of Glucagon-Like Peptides ..................... 565 Rhonda D. Wideman and Timothy J. Kieffer IV. CALCIUM-DEPENDENT SIGNALING .......................... 587 20. Control of Intracellular Calcium Levels.............................. 589 Shyamala Dakshinamurti, Jonathan Geiger, and Krishnamurti Dakshinamurti 21. Calcium-Mediated Signaling of Neurons in the Physiological and Diseased State: Role of Endoplasmic Reticulum ............................................................................... 621 Wulf Paschen V. FEEDING AND NUTRIENT HOMEOSTASIS .............. 639 22. Within-Meal Feedback Signaling ......................................... 641 Jason C.G. Halford 23. The Arcuate Nucleus: Its Special Place in the Brain Networks that Control Feeding Behavior ........................... 665 Bernard Beck Index................................................................................................