Predictive toxicology
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Christoph Helma
- ناشر : Boca Raton : Taylor & Francis
- چاپ و سال / کشور: 2005
- شابک / ISBN : 9780824723972
Description
A brief introduction to predictive toxicology / Christoph Helma -- Description and representation of chemicals / Wolfgang Guba -- Computational biology and toxicogenomics / Kathleen Marchal ... [et al.] -- Toxicological information for use in predictive modelig: quality, sources, and databases / Mark T.D. Cronin -- The use of expert systems for toxicology risk prediction / Simon Parsons and Peter McBurney -- Regression- and projection-based approaches in predictive toxicology / Lennart Eriksson, Erik Johansson, and Torbjörn Lundstedt -- Machine learning and data mining / Stefan Kramer and Christoph Helma -- Neural networks and kernel machines for vector and structured data / Paolo Frasconi -- Applications of substructure-based SAR in toxicology / Herbert S. Rosenkranz and Bhavani P. Thampatty -- OncoLogic: a mechanism-based expert system for predicting the carcinogenic potential of chemicals / Yin-Tak Woo and David Y. Lai -- META: an expert system for the prediction of metabolic transformations / Gilles Klopman and Aleksandr Sedykh -- MC4PC - an artificial intelligence approach to the discovery of quantitative structure-toxic activity relationships / Gilles Klopman ... [et al.] -- PASS: prediction of biological activity spectra for substances / Vladimir Poroikov and Dmitri Filimonov -- Iazar: lazy structure-activity relationships for toxicity prediction / Christoph Helma.
A comprehensive overview of techniques and systems currently utilized, this reference presents an in-depth survey of strategies to characterize chemical structures and biological systems - covering prediction methods and algorithms, sources of high-quality toxicity data, important commercial and non-commercial predictive toxicology.
