Metabonomics in toxicity assessment
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Donald G Robertson; John C Lindon
- ناشر : Boca Raton, FL : Taylor & Francis
- چاپ و سال / کشور: 2005
- شابک / ISBN : 9780824726652
Description
An overview of metabonomics / John C. Lindon, Elaine Holmes, and Jeremy K. Nicholson -- Overview of biomarkers / John Timbrell -- NMR spectroscopy : principles and instrumentation / Michael D. Reily and John C. Lindon -- NMR spectroscopy of biofluids / John C. Lindon, Jeremy K. Nicholson, and Elaine Holmes -- 1H magic angle spinning NMR spectroscopy of tissues / Julian L. Griffin ... [et al.] -- The application of metabonimics as an early in vivo toxicity screen / Gregory J. Stevens, Alan J. Deese, and Donald G. Robertson -- Strategies and techniques for the identification of endogenous and xenobiotic metabolites detected in metabonomic studies / John Shockcor and Ian D. Wilson -- Multi- and megavariate data analysis : finding and using regularities in metabonimics data / Lennart Eriksson ... [et al.] -- Use of metabonomics to study target organ toxicity / Craig E. Thomas, Elaine Holmes, and Donald G. Robertson -- Physiological variation in laboratory animals and humans / M.E. Bollard ... [et al.] -- Environmental applications of metabonomic profiling / Jacob G. Bundy -- Current challenges and future developments in metabonomics technology / Donald G. Robertson.
Handbook outline the use of metabonomics in the safety assessment of new chemical entities.
