Protein folding, misfolding and aggregation : classical themes and novel approaches
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Victor Muñoz
- ناشر : Cambridge, UK : Royal Society of Chemistry
- چاپ و سال / کشور: 2008
- شابک / ISBN : 9780854042579
Description
The [alpha]-helix as the simplest protein model : helix-coil theory, stability, and design -- Kinetics and mechanisms of [alpha]-helix formation -- The protein folding energy landscape : a primer -- Hydrogen exchange experiments : detection and characterization of protein folding intermediates -- Statistical differential scanning calorimetry : probing protein folding-unfolding ensembles -- Fast protein folding -- Single molecule spectroscopy in protein folding: from ensembles to single molecules -- Computer simulations of protein folding -- Protein design : tailoring sequence, structure, and folding properties -- Protein misfolding and [beta]-amyloid formation -- Scenarios for protein aggregation : molecular dynamics simulations and bioinformatics analysis
This unique book covers all the modern approaches and the many advances experienced in the field of protein folding and aggregation during the last 10 years.
