Bioinformatics methods and protocols
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Stephen Misener; Stephen A Krawetz
- ناشر : Totowa, N.J. : Humana Press
- چاپ و سال / کشور: 2000
- شابک / ISBN : 9780896037328 .
Description
Introduction: The Role of Genetic Bioinformatics / Michael R. Barnes, Ian C. Gray -- Genetics in the post-genome era--the role of bioinformatics -- Knowledge management and expansion -- Data management and mining -- Genetic study designs -- Physical locus analysis -- Selecting candidate genes for analysis -- Progressing from candidate gene to disease-susceptibility gene -- Comparative genetics and genomics -- Internet Resources for the Geneticist / Michael R. Barnes, Christopher Southan -- Sub-division of biological data on the internet -- Searching the internet for genetic information -- Which web search engine? -- Search syntax: the mathematics of search engine use -- Boolean searching -- Searching scientific literature--getting to 'state of the art' -- Searching full-text journals -- Searching the heart of the biological internet--sequences and genomic data -- Nucleotide and protein sequence databases -- Biological sequence databases--primary and secondary -- Human Genetic Variation: Databases and Concepts / Michael R. Barnes -- Forms and mechanisms of genetic variation -- Databases of human genetic variation -- SNP databases -- Mutation databases -- Genetic marker and microsatellite databases -- Non-nuclear and somatic mutation databases -- Tools for SNP and mutation visualization--the genomic context -- Tools for SNP and mutation visualization--the gene context -- Finding, Delineating and Analysing Genes / Christopher Southan -- The evidence cascade for gene products -- Shortcomings of the standard gene model.
