Recombinant antibodies for cancer therapy : methods and protocols

Generation of antibody molecules through antibody engineering / S.M. Kipriyanov -- Application of recombinant antibodies in cancer patients / J. Krauss, M. Arndt and M. Pfreundschuh -- DNA immunization as a means to generate antibodies to proteins / P.S. Chowdhury -- Chimerization of a monoclonal antibody for treating hodgkin's lymphoma / J. Krauss ... [et al.] -- Humanization of monoclonal antibodies by CDR grafting / S. O'Brien and T. Jones -- Generation and screening of a modular human scfv expression library from multiple donors / M. Welschof ... [et al.] -- Construction of semisynthetic antibody libraries / M. Braunagel -- Single-domain vh antibody fragments from a phage display library / L. Binyamin, D. Plaksin and Y. Reiter -- Isolation of human fab fragments against ovarian carcinoma using guided selection / M. Figini ... [et al.] -- Human recombinant fab antibodies with t-cell receptor-like specificities generated from phage display libraries / J. Engberg ... [et al.] -- Engineering hot spots for affinity enhancement of antibodies / P.S. Chowdhury -- Simultaneous humanization and affinity optimization of monoclonal antibodies / H. Wu -- Tailoring kinetics of antibodies using focused combinatorial libraries / H. Wu and L.L. An -- Engineering scfvs for improved stability / P.S. Chowdhury and G. Vasmatzis -- Recombinant single-chain and disulfide-stabilized fv immunotoxins for cancer therapy / R. Niv, D. Segal and Y. Reiter -- Generation of recombinant immunotoxins for specific targeting of tumor-related peptides presented by mhc molecules / C.J. Cohen ... [et al.] -- Construction and characterization of rnase-based targeted therapeutics / D.L. Newton ... [et al.] -- Bispecific diabodies for cancer therapy / M. Arndt and J. Krauss -- Generation and characterization of bispecific tandem diabodies for tumor therapy / S.M. Kipriyanov -- Generation of recombinant multimeric antibody fragments for tumor diagnosis and therapy / B.E. Power, A.A. Kortt and P.J. Hudson -- Construction and characterization of minibodies for imaging and therapy of colorectal carcinomas / P.J. Yazaki and A.M. Wu -- Generation, expression, and monitoring of recombinant immune receptors for use in cellular immunotherapy / A. Hombach, C. Heuser and H. Abken -- Tailoring natural effector functions. Antibody engineering beyond humanization / O.H. Brekke and J.E. Thommesen -- Single-chain fv-based affinity purification of the cellular stress protein gp96 for vaccine development / C. Kleist ... [et al.] -- Recombinant adenoviruses for in vivo expression of antibody fragments / R.E. Kontermann, T. Korn and V. Jerome -- Production of antibody fragments in a bioreactor / H. Hellebust -- Large scale production of recombinant antibodies by utilizing cellulose-binding domains / I. Benhar and Y. Berdichevsky -- Production of tumor-specific antibodies in tobacco / C. Vaquero-Martin and R. Fischer