Oxidation : the cornerstone of carcinogenesis
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : John C Stavridis
- ناشر : Dordrecht ; London : Springer,
- چاپ و سال / کشور: 2008
- شابک / ISBN : 9781402067044
Description
Chapter 1: Oxygen and Nitrogen free radicals Chapter 2: Oxidative stress Chapter 3: Oxidative damage of genome DNA: repair mechanisms Chapter 4: Mitochondria: structure, function and relationship with carcinogenesis Chapter 5: Oxidative activation of transcription factor pathways by cigarette smoke oxidants Chapter 6: Cell protection mechanisms from oxidation Chapter 7: Role of DNA adducts in carcinogenesis Chapter 8: Transmolecular reactions of genetic toxicity: alkylation and methylation of DNA Chapter 9: Toxicity and carcinogenicity of hydrocarbons Chapter 10: Toxicity and carcinogenicity of the aromatic hydrocarbons Chapter 11: Toxicity and carcinogenicity of aldehydes Chapter 12: Toxicity and carcinogenicity of the nitriles Chapter 13: Toxicity and carcinogenicity of the eterocyclic organic compounds Chapter 14: Toxicity and carcinogenicity of metals Chapter 15:Oxidative profile of cigarette smoke and lung cancer Chapter 16: Smoking and lung cancer
"In order to learn oncology, it is necessary to acquire a comprehensive knowledge of molecular biology in carcinogenesis, and then, with this as a background, to consider the principles of the theoretical and clinical basis of the subject. For graduate students who are preparing themselves for the specialty of internal medicine or clinical oncology, and physicians who wish to become proficient in oncology, it is exceedingly difficult to be highly skilled and completely informed in this expanding field of science without a comprehensive text on the subject. This book is unique, due to its collective approach to the key aspects of the interdependency between three entities: oxidative stress, tobacco smoke and carcinogenesis, operating in a cause-effect sequence, in a concise and to the point manner. I hope this book will prove to be a helpful companion to the internist, the oncologist and the research scientist in molecular biology as well as a work of reference for the general practitioner and physician interested in cancer research."--Jacket
