Lung transplantation

Preface . . . vii Contributors . . . . . ix Part I General 1. The History of Lung Transplantation . . . . . . . . . . . . . . . . . . 1 Raja Mahidhara and John R. Benfield 2. Immunology of Lung Transplantation . . . . . . . . . . . . . . . . . 8 Rebecca A. Shilling and David S. Wilkes 3. Ethics in Lung Transplantation . . . . . . . . . . . . . . . . . . . . . 17 Savitri E. Fedson and Mark Siegler 4. Structure and Support for Success . . . . . . . . . . . . . . . . . . . 27 Wickii T. Vigneswaran Part II Pretransplant Evaluation and Management 5. Lung Transplantation for Idiopathic Pulmonary Fibrosis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34 Jeffrey T. Chapman and Atul C. Mehta 6. Emphysema and a-1 Antitrypsin Deficiency . . . . . . . . . . . . 47 Martin R. Zamora 7. Cystic Fibrosis and Bronchiectasis . . . . . . . . . . . . . . . . . . . 58 Elliott Dasenbrook and Christian Merlo xv 8. Pulmonary Arterial Hypertension . . . . . . . . . . . . . . . . . . . 65 Stuart Rich 9. Connective Tissue Disorders . . . . . . . . . . . . . . . . . . . . . . . 75 Vincent G. Valentine and Gisele A. Lombard 10. Patient Selection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 Eric Stern and Edward R. Garrity, Jr. 11. Recipient Management Pretransplant . . . . . . . . . . . . . . . . . 99 Hilary Y. Robbins and Selim M. Arcasoy Part III Donor Management 12. Lung Donor Allocation Systems . . . . . . . . . . . . . . . . . . . . . 105 Thomas M. Egan 13. Donor Management . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115 Anthony Rostron and John H. Dark 14. Lung Donor Selection Criteria . . . . . . . . . . . . . . . . . . . . . . 125 Sang-Woo Pak and Joshua Sonett 15. Non-Heart-Beating Donor: Lung Transplantation with Donation After Cardiac Death (Controlled DCD) Allografts . . . . . . . 135 Christopher H. Wigfield, Jason W. Smith, and Robert B. Love 16. Preservation of the Donor Lung . . . . . . . . . . . . . . . . . . . . . 145 Marcelo Cypel, Jonathan C. Yeung, and Shaf Keshavjee 17. Donor Procurement . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 154 Hassan W. Nemeh 18. Ex Vivo Management of Lungs . . . . . . . . . . . . . . . . . . . . . 160 Dirk Van Raemdonck, Filip Rega, and Arne Neyrinck xvi Contents Part IV Recipient Operation 19. Assessment and Management of the Sensitized Patient . . . . 168 Kevin M. Chan and Malek Kamoun 20. Anesthesia for Lung Transplantation . . . . . . . . . . . . . . . . . 180 Mohammed Minhaj and Mark Chaney 21. Single-Lung Transplantation . . . . . . . . . . . . . . . . . . . . . . . 190 Gabriel Loor and Wickii T. Vigneswaran 22. Bilateral Sequential Lung Transplantation: Technical Aspects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 198 Varun Puri and G. Alexander Patterson 23. Heart-Lung Transplantation . . . . . . . . . . . . . . . . . . . . . . . 208 William M. Yarbrough, Robert C. Robbins, and Hari R. Mallidi 24. Lobar Lung Transplantation . . . . . . . . . . . . . . . . . . . . . . . 217 Michael E. Bowdish, Vaughn A. Starnes, and Mark L. Barr Part V Post-transplant Care 25. Critical Care Management . . . . . . . . . . . . . . . . . . . . . . . . 224 Peter Jaksch, Herbert Koinig, and Walter Klepetko 26. Primary Graft Dysfunction . . . . . . . . . . . . . . . . . . . . . . . . 237 James C. Lee and Jason D. Christie 27. Managing Surgical Complications . . . . . . . . . . . . . . . . . . . 249 Ilhan Inci and Walter Weder 28. ECMO in Lung Transplantation . . . . . . . . . . . . . . . . . . . . 266 R. Duane Davis and Shu S. Lin Part VI Early Medical Management 29. Maintenance Immunosuppression in Lung Transplantation . . . . . . . . . . . . . . . . . . . . . . . . . . . . 272 Pamela J. McShane and Sangeeta M. Bhorade Contents xvii 30. Fungal Infections in Lung Transplant . . . . . . . . . . . . . . . . 285 Ayesha Haroon and Shahid Husain 31. Viral Infections . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 297 Lara A. Danziger-Isakov, Marie Budev, and Robin K. Avery 32. Bacterial Infections After Lung Transplantation . . . . . . . . . 311 Charulata Ramaprasad and Kenneth Pursell 33. Post-Transplant Lung Pathology . . . . . . . . . . . . . . . . . . . . 320 Ilyssa O. Gordon and Aliya N. Husain Part VII Late Medical Management and Outcome 34. Bronchiolitis Obliterans Syndrome: Clinical Risk Factors and Pathophysiology . . . . . . . . . . . . . 328 Christine V. Kinnier, Tereza Martinu, and Scott M. Palmer 35. Bronchiolitis Obliterans: Diagnosis and Management . . . . . 336 Pali D. Shah and Jonathan B. Orens 36. Malignancy Following Transplantation . . . . . . . . . . . . . . . . 347 Chien-Li Liew and Allan R. Glanville 37. Lung Transplantation: Chronic Complications and Management . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 357 Keith C. Meyer 38. Quality of Life After Lung Transplantation . . . . . . . . . . . . 375 James C. Lee, Nancy P. Blumenthal, and Vivek N. Ahya Part VIII Future Directions 39. Proteomics, Genomics, and Lung Transplantation . . . . . . . 383 Jeffrey D. Edelman and Michael S. Mulligan 40. Immune Tolerance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 390 Kenneth R. McCurry xviii Contents 41. Augmentation of Maintenance Immunosuppression in Lung Transplantation . . . . . . . . . . . . . . . . . . . . . . . . . . 398 Pamela J. McShane and Sangeeta M. Bhorade 42. Artificial Lung: A New Inspiration . . . . . . . . . . . . . . . . . . 413 James E. Lynch and Joseph B. Zwischenberger Index . . . . 423