The Rho GTPases in cancer
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Kenneth van Golen
- ناشر : New York : Springer
- چاپ و سال / کشور: 2010
- شابک / ISBN : 9781441911117
Description
1 Overview of Rho GTPase History ........................................................... 3 Ellen V. Stevens and Channing J. Der 2 Rho Proteins in Cancer............................................................................. 29 Devin T. Rosenthal, John Chadwick Brenner, and Sofi a D. Merajver Part II The Rho Regulatory Proteins in Cancer 3 RhoGDIs in Cancer ................................................................................... 45 Anthony N. Anselmo, Gary M. Bokoch, and Céline DerMardirossian 4 Signaling through Galpha12/13 and RGS-RhoGEFs ............................ 59 Nicole Hajicek, Barry Kreutz, and Tohru Kozasa 5 Vav Proteins in Cancer ............................................................................. 77 Daniel D. Billadeau 6 Rho GTPase-Activating Proteins in Cancer ........................................... 93 Matthew W. Grogg and Yi Zheng Part III The Rho GTPase Proteins and Cancer 7 RhoBTB Proteins in Cancer..................................................................... 111 Caroline McKinnon and Harry Mellor 8 RhoC GTPase in Cancer Progression and Metastasis ........................... 123 Kenneth van Golen 9 RhoB GTPase and FTIs in Cancer .......................................................... 135 Minzhou Huang, Lisa D. Laury-Kleintop, and George C. Prendergast x Contents 10 Regulation of Rho GTPase Activity Through Phosphorylation Events: A Brief Overview .......................................... 155 Heather Unger and Kenneth van Golen 11 The Rho-Regulated ROCK Kinases in Cancer .................................... 163 Grant R Wickman, Michael Samuel, Pamela A Lochhead, and Michael F Olson Author Index.................................................................................................... 193 Subject Index ................................................................................................... 203