Cell cycle deregulation in cancer
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Greg H Enders
- ناشر : New York : Springer
- چاپ و سال / کشور: 2010
- شابک / ISBN : 9781441917690
Description
Starting the cell division cycle Elena Sotillo and Xavier Grana Escape from cellular quiescence Jun-Yuan Ji and Nicholas J. Dyson Interplay between Cyclin-dependent Kinases and E2F-dependent Transcription. A. Kathleen McClendon, Jeffry L. Dean, and Erik S. Knudsen Regulation of pre-RC assembly: A complex symphony orchestrated by CDKs Proliferation under duress Haomin Huang and Timothy J Yen Mitotic checkpoint and chromosome instability in cancer Jeremy P.H. Chow and Randy Y.C. Poon Mitotic catastrophe Robert D. Hontz and Maureen E. Murphy p53, ARF and the control of autophagy Long-term proliferation Andrea Viale and Pier Giuseppe Pelicci Regulation of self-renewing divisions in normal and leukaemia stem cells Eros Lazzerini Denchi Maintenance of Telomeres in Cancer Peter D. Adams The senescence secretome and its impact on tumor suppression and cancer Applications in preventing and treating cancer Pierre Lao-Sirieix and Rebecca C Fitzgerald Cell cycle deregulation in pre-neoplasia: case study of Barrett's esophagus Neil Johnson and Geoffrey I. Shapiro Targeting cyclin dependent kinases for cancer therapy
This collection of 11 reviews shows how cells initiate the cell cycle, describes issues of proliferation, discusses long-term proliferation and relates the uses of cell cycle research in assessment of pre-malignant states and in cancer therapy
