Windows to the Brain : Insights From Neuroimaging

CONTRIBUTORS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xv FOREWORD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xix Stuart C. Yudofsky, M.D., and Robert E. Hales, M.D., M.B.A. PREFACE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xxiii Robin A. Hurley, M.D., and Katherine H. Taber, Ph.D. Part 1 IMAGING TECHNIQUES Chapter 1 BLOOD FLOW IMAGING OF THE BRAIN: 50 YEARS’ EXPERIENCE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Katherine H. Taber, Ph.D. Kevin J. Black, M.D. Robin A. Hurley, M.D. Chapter 2 FUNCTIONAL MAGNETIC RESONANCE IMAGING: APPLICATION TO POSTTRAUMATIC STRESS DISORDER . . . . . . . . . . . . . . . . 11 Katherine H. Taber, Ph.D. Scott L. Rauch, M.D. Ruth A. Lanius, M.D., Ph.D., F.R.C.P.C. Robin A. Hurley, M.D. Chapter 3 ECSTASY IN THE BRAIN: A MODEL FOR NEUROIMAGING. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 Robin A. Hurley, M.D. Liesbeth Reneman, M.D. Katherine H. Taber, Ph.D. Chapter 4 THE FUTURE FOR DIFFUSION TENSOR IMAGING IN NEUROPSYCHIATRY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 Katherine H. Taber, Ph.D. Carlo Pierpaoli, M.D., Ph.D. Stephen E. Rose, Ph.D. Fergus J. Rugg-Gunn, M.D. Jonathan B. Chalk, M.B.B.S., F.R.A.C.P., Ph.D. Derek K. Jones, Ph.D. Robin A. Hurley, M.D Chapter 5 CORTICAL INHIBITION IN ALCOHOL DEPENDENCE . . . . . . . . . . . . .33 Katherine H. Taber, Ph.D. Robin A. Hurley, M.D. Anissa Abi-Dargham, M.D. Bernice Porjesz, M.D. Chapter 6 APPLICATION OF MAGNETOENCEPHALOGRAPHY TO THE STUDY OF AUTISM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .39 Robin A. Hurley, M.D. Jeffrey David Lewine, Ph.D. Gregory M. Jones, Ph.D. William W. Orrison Jr., M.D. Katherine H. Taber, Ph.D. Chapter 7 APPLICATIONS OF XENON COMPUTED TOMOGRAPHY IN CLINICAL PRACTICE: DETECTION OF HIDDEN LESIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 Katherine H. Taber, Ph.D. Jana G. Zimmerman, Ph.D. Howard Yonas, M.D. William Hart, B.S.R.S., R.T. Robin A. Hurley, M.D. Chapter 8 NEW TECHNIQUES FOR UNDERSTANDING HUNTINGTON’S DISEASE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .49 Robin A. Hurley, M.D. Edward F. Jackson, Ph.D. Ronald E. Fisher, M.D., Ph.D. Katherine H. Taber, Ph.D. Part 2 SPECIFIC DISEASES Chapter 9 SUDDEN ONSET PANIC: EPILEPTIC AURA OR PANIC DISORDER?. . . . . . . . . . . . . . . . . . . . . . . . . . . 57 Robin A. Hurley, M.D. Ronald E. Fisher, M.D., Ph.D. Katherine H. Taber, Ph.D. Chapter 10 BIPOLAR DISORDER: IMAGING STATE VERSUS TRAIT. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67 Jacqueline N.W. Friedman, Ph.D. Robin A. Hurley, M.D. Katherine H. Taber, Ph.D. Chapter 11 BLAST-RELATED TRAUMATIC BRAIN INJURY: WHAT IS KNOWN? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 75 Katherine H. Taber, Ph.D. Deborah L. Warden, M.D. Robin A. Hurley, M.D. Chapter 12 MILD TRAUMATIC BRAIN INJURY: NEUROIMAGING OF SPORTS-RELATED CONCUSSION . . . . . . . . . . . . . . . . . 83 Cecilia V. Mendez, M.D. Robin A. Hurley, M.D. Maryse Lassonde, Ph.D. Liying Zhang, Ph.D. Katherine H. Taber, Ph.D. Chapter 13 TRAUMATIC AXONAL INJURY: NOVEL INSIGHTS INTO EVOLUTION AND IDENTIFICATION . . . . . . . . . . . . . . 91 Robin A. Hurley, M.D. Joseph C. McGowan, Ph.D. Konstantinos Arfanakis, Ph.D. Katherine H. Taber, Ph.D. Chapter 14 FUNCTIONAL IMAGING AS A WINDOW TO DEMENTIA: CORTICOBASAL DEGENERATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .99 Andreea L. Seritan, M.D. Mario F. Mendez, M.D., Ph.D. Daniel H.S. Silverman, M.D., Ph.D. Robin A. Hurley, M.D. Katherine H. Taber, Ph.D. Chapter 15 METACHROMATIC LEUKODYSTROPHY: A MODEL FOR THE STUDY OF PSYCHOSIS. . . . . . . . . . . . . . . . . . . . . . . . 107 Deborah N. Black, M.D. Katherine H. Taber, Ph.D. Robin A. Hurley, M.D.