1-58829-143-X
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Arne Schousboe; Hans Bräuner-Osborne
- ناشر : Totowa, N.J. : Humana Press
- چاپ و سال / کشور: 2004
- شابک / ISBN : 9781588291431
Description
Pt. I. Molecular pharmacology of glutamate receptors. Computational studies of ligand-receptor interactions in ionotropic glutamate receptors / Jeremy R. Greenwood and Tommy Liljefors -- Delineation of the physiological role of kainate receptors by use of subtype selective ligands / Sari E. Lauri, Vernon R.J. Clarke, and Graham L. Collingridge -- Molecular pharmacology fo the metabotropic glutamate receptors / Anders A. Jensen -- Pt. II. Molecular pharmacology of GABA receptors. Functional characterization of GABA receptor ligands in virtro: correlation with in vivo activity / Bjarke Ebert ... [et al.] -- In vivo function of GABA receptor subtypes unraveled with mutant mice / Jean-Marc Fritschy -- Characterization of the GABA receptor recognition site through ligand design and pharmacophore modeling / Bente Frølund ... [et al.] -- The GABA receptor: from cloning to knockout mice / Bernhard Bettler and Hans Bräuner-Osborne -- Pt. III. Molecular pharmacology of transmitter transporters. Structure and molecular characterization of the substrate-binding sites of the dual-function glutamate transporters / Baruch I. Kanner, Michael P. Kavanaugh, and Lars Borre -- Allosteric modulation of glutamate transporters / Robert J. Vandenberg and Renae M. Ryan -- Characterization of the substrate-binding site in GABA transporters / Alan Sarup, Orla Miller Larsson, and Arne Schousboe -- Insights from endogenous and engineered Zn²⁺ binding sites in monoamine transporters / Claus Juul Loland and Ulrik Gether -- A structural context for studying neurotransmitter transporter function / Naomi R. Goldberg ... [et al.] -- Functional mechanisms of g protein-coupled receptors in a structural context
