Proteomics in Drug Research.

Proteomics in Drug Research.

  • نوع فایل : کتاب
  • زبان : انگلیسی
  • مؤلف : Michael Hamacher; Katrin Marcus; Kai Sthler
  • ناشر : Weinheim : Wiley-VCH
  • چاپ و سال / کشور: 2006
  • شابک / ISBN : 9783527607945

Description

Administrative optimization of proteomics networks for drug development / André van Hall, Michael Hamacher -- Proteomic data standardization, deposition and exchange / Sandra Orchard, Henning Hermjakob, Manuela Pruess, Rolf Apweiler -- Difference gel electrophoresis (DIGE) : the next generation of two-dimensional gel electrophoresis for clinical research / Barbara Sitek, Burghardt Scheibe, Klaus Jung, Alexander Schramm, Kai Stühler -- Biological mass spectrometry : basics and drug discovery related approaches / Bettina Warscheid -- Multidimensional column liquid chromatography (LC) in proteomics : where are we now? / Egidijus Machtejevas, Klaus K. Unger, Reinhard Ditz -- Peptidomics technologies and applications in drug research / Michael Schrader, Petra Budde, Horst Rose, Norbert Lamping, Peter Schulz-Knappe, Hans-Dieter Zucht -- Protein biochips in the proteomic field / Angelika Lücking, Dolores J. Cahill -- Current developments for the in vitro characterization of protein interactions / Daniela Moll, Bastian Zimmermann, Frank Gesellchen, Friedrich W. Herberg -- Molecular networks in morphologically intact cells and tissue-challenge for biology and drug development / Walter Schubert, Manuela Friedenberger, Marcus Bode -- From target to lead synthesis / Stefan Müllner, Holger Stark, Päivi Niskanen, Erich Eigenbrodt, Sybille Mazurek, Hugo Fasold -- Differential phosphoproteome analysis in medical research / Elke Butt, Katrin Marcus -- Biomarker discovery in renal cell carcinoma applying proteome-based studies in combination with serology / Barbara Seliger, Roland Kellner -- Studies of drug resistance using organelle proteomics / Catherine Fenselau, Zongming Fu -- Clinical neuroproteomics of human body fluids : CSF and blood assays for early and differential diagnosis of dementia / Jens Wiltfang, Piotr Lewczuk -- Proteomics in Alzheimer's disease / Michael Fountoulakis, Sophia Kossida, Gert Lubec -- Cardiac proteomics / Emma McGregor, Michael J. Dunn -- Innovation processes / Sven Rüger.
From skillful handling of the wide range of technologies to successful applications in drug discoverythis handbook has all the information professional proteomics users need. Edited by experts working at one of the hot spots in European proteomic research, the numerous contributions by experts from the pharmaceutical industry and public proteomics consortia to provide the necessary perspective on current trends and developments in this exciting field. Following an introductory chapter, the book moves on to proteomic technologies, such as protein biochips, protein-protein interactions, and pro.
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