Dermal absorption
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : J Kielhorn; Stephanie Melching-Kollmuss; I Mangelsdorf; World Health Organization.; International Labour Organisation.; Inter-Organization Programme f
- ناشر : Geneva : World Health Organization
- چاپ و سال / کشور: 2006
- شابک / ISBN : 9789241572354
Description
1. Summary -- 2. Introduction and definitions -- 3. Skin structure and function -- 4. Skin transport mechanisms and theoretical concepts -- 5. Metabolism in the skin -- 6. In vitro tests for dermal absorption -- 7. In vivo tests for dermal absorption -- 8. Comparative studies -- 9. Data collections -- 10. Estimation/Prediction of dermal penetration -- 11. Use of dermal penetration studies in risk assessment -- 12. Controversial topics in the assessment of dermal absorption -- 13. Conclusions and recommendations -- References -- Appendix 1. Guidelines and protocols -- Appendix 2. Past and present initiatives on exchange of information and harmonization of methodology on dermal absorption