Quinacrine sterilization: experience among women at high risk for surgery
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : A.R. SARIN
- چاپ و سال / کشور: 2000
Description
A non-surgical method of female sterilization is needed because many women are at high risk of complications with standard surgical methods, especially in developing countries. Also, some women who desire sterilization refuse it for fear of surgery. To meet these special needs, we initiated a trial of quinacrine sterilization (QS), a non-surgical method involving transcervical insertion of 252 mg quinacrine as pellets by a modi¢ed IUD inserter. Diclofenac (50 mg) was inserted with the quinacrine pellets. This insertion was repeated a month later and a 150-mg injection of depo medroxyprogesterone was administered at the time of the ¢rst insertion. One hundred and thirty-four women of reproductive age entered the trial. Of these, 92 were considered to be at high risk for surgery, 27 had refused surgery, and 15 had had failed surgical sterilization. Mean follow-up was 3.46 years. No pregnancies or serious complications were experienced. The main side-e،ect was menstrual irregular- ity, due probably to the depo medroxyprogesterone injection. QS is a suitable option for women at high risk of surgical complications.
Advances in Contraception, 1999; 15: 175^178. #2000Kluwer Academic Publishers. Printed in theNetherlands
