Profile of French Community-Dwelling Older Adults Supplemented with Vitamin D: Findings and Lessons
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Bruno Fantino , Olivier Beauchet , Séverine Savignat , Béatrice Bouvard , Erick Legrand , Cédric Annweiler
- چاپ و سال / کشور: 2011
Description
Introduction: The vast majority of older French adults exhibit some degree of hypovitaminosis D. The objective of this cross-sectional study was to determine the rate and the reasons for vitamin D prescription among older French adult community dwellers. Methods: Vitamin D supplementation was systematically assessed among 1876 French community dwellers aged .65 years. Theoretical indications for vitamin D supplementation were collected, ie, the causes of hypovitaminosis D (older age, male gender, kidney failure, undernutrition, polymorbidity) or its clinical complications (vertebral or nonvertebral fractures, gait disturbances, history of falls, muscle weakness, and cognitive impairment). Results: In total, 13.8% of the subjects (n=258) had vitamin D supplementation. They were more often malnourished (P=0.002), exhibited polymorbidity (P<0.001) and muscle weakness (P<0.001), and had a history of vertebral fractures (P<0.001), non-vertebral fractures (P<0.001), and accidental falls (P<0.001). Vitamin D supplementation was explained by the number of complications of hypovitaminosis D (odds ratio [OR]=1.61, P<0.001) including vertebral fractures (adjusted OR=1.49, P=0.007), non-vertebral fractures (adjusted OR=1.74, P=0.026), accidental falls (adjusted OR=1.44, P=0.015), and muscle weakness (adjusted OR=3.96, P<0.001), but not by the number of causes of hypovitaminosis D (P=0.464). Conclusion: Even if vitamin D supplementation is selected well for appropriate patients, the rate of supplementation remains insufficient in France, and probably comes too late, ie, at the stage of complications of hypovitaminosis D. These findings should encourage physicians to supplement vitamin D more often and sooner in their elderly patients.
Adv Ther (2011) 28(6):483-489. DOI 10.1007/s12325-011-0030-4 Received: March 25, 2011 / Published online: May 19, 2011
