Immunocytochemical study of glycine receptors in the retina of the frog Xenopus laevis

Immunocytochemical study of glycine receptors in the retina of the frog Xenopus laevis

  • نوع فایل : کتاب
  • زبان : انگلیسی
  • مؤلف : Lily Vitanova
  • چاپ و سال / کشور: 2006

Description

The expression of glycine receptors in the retina of clawed frog, Xenopus laevis was studied immunocytochemically. Glycine receptors (GlyRs), as revealed by means of several different antibodies, were mainly distributed in the inner (IPL) and the outer plexiform layers. Their composition was determined to include a2 and a3 subunits. Typical punctate appearance and specific lamination in the IPL were seen with each of the antibodies directed against the different GlyRs’ subunits. A notion for diversity of the glycine receptors was put forward, according to which the a2 and a3 subunits are located in different subtypes of glycine synapses.
Anat Embryol (2006) 211: 237–245 Accepted: 15 December 2005 / Published online: 17 January 2006
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