On periodicity and directionality of somitogenesis
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Alexander Aulehla Æ Olivier Pourquie
- چاپ و سال / کشور: 2006
Description
It is currently thought that the mechanism underlying somitogenesis is linked to a molecular oscillator, the segmentation clock, and to gradients of signaling molecules within the paraxial mesoderm. Here, we review the current picture of this segmentation clock and gradients, and use this knowledge to critically ask: What is the basis for periodicity and directionality of somitogenesis?
Anat Embryol (2006) 211 (Suppl. 1): S3–S8 Accepted: 17 August 2006 / Published online: 21 September 2006