Hepatic falciform ligament Tc-99m-macroaggregated albumin activity on SPECT/CT prior to Yttrium-90 microsphere radioembolization: prophylactic measures to prevent non-target microsphere localization via patent hepatic falciform arteries
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Yung Hsiang Kao Andrew E. H. Tan Li Ser Khoo Richard H. G. Lo Pierce K. H. Chow Anthony S. W. Goh
- چاپ و سال / کشور: 2011
Description
Yttrium-90 (Y-90) selective internal radiation therapy (SIRT) is increasingly used to treat inoperable hepatocellular carcinoma. We describe two patients where hepatic falciform ligament Technetium-99m-macroaggregated albumin (Tc-99m-MAA) activity was identified on single photon emission computed tomography with integrated low-dose CT (SPECT/CT) scan during pretherapy planning, and the steps taken to prevent radiation dermatitis. The first patient underwent prophylactic coil embolization of the patent hepatic falciform artery; the second patient underwent super-selective infusion of Y-90 resin microspheres to avoid the patent hepatic falciform artery. The incidence of falciform ligament Tc-99m-MAA activity detected on SPECT/CT at our institution is 10%. Tc-99m-MAA SPECT/CT scan provides valuable diagnostic information for treatment planning prior to Y-90 SIRT.
Ann Nucl Med (2011) 25:365–369 DOI 10.1007/s12149-010-0464-9 Received: 7 November 2010 / Accepted: 16 December 2010 / Published online: 14 January 2011
