Intestinal uptake of 99mTc-MDP: a case report of protein-losing enteropathy correlated with pathology findings from autopsy

Intestinal uptake of 99mTc-MDP: a case report of protein-losing enteropathy correlated with pathology findings from autopsy

  • نوع فایل : کتاب
  • زبان : انگلیسی
  • مؤلف : Begonکa Martinez-Sanchis Virginia Corte´s-Vizca‎´no Lorena Frontado-Morales Pablo Sopena-Novales
  • چاپ و سال / کشور: 2010

Description

We present a case of a 60-year-old man with a history of severe hypoproteinemia and constitutional syndrome, suspected to have protein-losing enteropathy (PLE). Bone scintigraphy (99mTc-MDP) performed to rule out the presence of bone metastases incidentally showed abnormal uptake in abdominal soft tissue. The patient unexpectedly died of heart failure, and autopsy revealed microscopic alterations consistent with PLE exclusively in the right colon, corresponding to the area of abnormal uptake. Few similar cases have been published, but none of them reported correlative pathological findings affecting the area of abnormal tracer uptake. In this case of PLE, 99mTc-MDP scintigraphy was a useful imaging method for localizing the site of protein loss, showing a focal area of alteration in the right colon. This finding could also have been of great help in case that surgery had been finally performed to control the protein loss.
Ann Nucl Med (2011) 25:139–141 DOI 10.1007/s12149-010-0445-z Received: 27 May 2010 / Accepted: 8 October 2010 / Published online: 26 November 2010
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