Cerebellopontine angle endodermal cyst presenting with hemifacial spasm

Cerebellopontine angle endodermal cyst presenting with hemifacial spasm

  • نوع فایل : کتاب
  • زبان : انگلیسی
  • مؤلف : Prasanna Karki Manoj Bohara Hajime Yonezawa Hiroshi Tokimura Hirofumi Hirano Ryosuke Hanaya Kazunori Arita
  • چاپ و سال / کشور: 2011

Description

Intracranial endodermal cysts presenting with hemifacial spasm (HFS) are extremely rare. We report a right cerebellopontine angle (CPA) endodermal cyst in a 56-year-old man who presented with a 6-month history of right-sided hemifacial spasm. Computed tomography revealed a homogenous, well-demarcated, hyperdense lesion extending from prepontine cistern to right CPA. Magnetic resonance imaging demonstrated a right CPA extra-axial cystic lesion protruding into Meckel’s cave, with compression of cranial nerves VII and VIII. Light brown, creamy cystic content was totally removed, and the thin cyst wall surrounding cranial nerves VII and VIII and the right vertebral artery was subtotally removed through the right lateral suboccipital approach. On microscopic examination, the cyst wall was composed of mono- to multilayered stratified epithelia, which were lined by ciliated or nonciliated cuboidal cells, with cilia showing the characteristic 9 ? 2 pattern. Immunohistochemistry showed positive staining of cells composing the cyst wall with carcinoembryonic antigen, epithelial membrane antigen, cytokeratin 8, and negative staining with cytokeratin 20, and S-100, thereby characterizing endodermal cyst. Postoperatively, the patient was free of facial spasm
Brain Tumor Pathol DOI 10.1007/s10014-011-0042-4 Received: 14 March 2011 / Accepted: 13 May 2011  The Japan Society of Brain Tumor Pathology 2011
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