Women’s interest in taking tamoxifen and raloxifene for breast cancer prevention: response to a tailored decision aid
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Angela Fagerlin Amanda J. Dillard Dylan M. Smith Brian J. Zikmund-Fisher Rosemarie Pitsch Jennifer B. McClure Sarah Greene Sharon Hensle
- چاپ و سال / کشور: 2011
Description
Although tamoxifen can prevent primary breast cancer, few women use it as a preventive measure. A second option, raloxifene, has recently been approved. The objective of the study was to determine women’s interest in tamoxifen and raloxifene after reading a decision aid (DA) describing the risks and benefits of each medication. Women with 5-year risk of breast cancer C 1.66 from two large health maintenance organizations were randomized to receive a DA versus usual care. After reading an on-line DA that discussed the risks and benefits of tamoxifen and raloxifene, women completed measures of risk perception, decisional conflict, behavioral intentions, and actual behavior related to tamoxifen and raloxifene. 3 months following the intervention, 8.1% of participants had looked for additional information about breast cancer prevention drugs, and 1.8% had talked to their doctor about tamoxifen and/or raloxifene. The majority, 54.7%, had decided to not take either drug, 0.5% had started raloxifene, and none had started tamoxifen. Participants were not particularly worried about taking tamoxifen or raloxifene and did not perceive significant benefits from taking these drugs. Over 50% did not perceive a change in their risk of getting breast cancer if they took tamoxifen or raloxifene. After reading a DA about tamoxifen and raloxifene, few women were interested in taking either breast cancer prevention drug.
Breast Cancer Res Treat (2011) 127:681–688 DOI 10.1007/s10549-011-1450-1 Received: 8 March 2011 / Accepted: 10 March 2011 / Published online: 26 March 2011 Springer Science+Business Media, LLC (outside the USA) 2011
