Failure of ovarian ablation with goserelin in a pre-menopausal breast cancer patient resulting in pregnancy: a case report and review of the literature
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : N. Hill Y. Madarnas
- چاپ و سال / کشور: 2011
Description
To report an unanticipated pregnancy during ovarian ablation treatment with goserelin (10.8 mg SC every 12 weeks) in a 26-year old female with breast cancer. Review of the current literature and reports in MEDLINE, PubMED, and EMBASE using searches with keywords ‘‘goserelin, pregnancy, breast cancer, breast neoplasms, fertility, ovarian ablation, gonadotropin releasing hormone agonists/analogs, leuprolide, pregnancy complications, teratogens’’ (July–September 2010). Only 3 other reports of failures with goserelin administration at ablative doses in breast cancer patients were discovered. For physicians and breast cancer patients using a GnRH analog, it is important to be aware of the possibility of inadequate ovarian function suppression and the potential for pregnancy
Breast Cancer Res Treat (2011) 129:265–268 DOI 10.1007/s10549-011-1542-y Received: 5 December 2010 / Accepted: 20 April 2011 / Published online: 4 May 2011
