Refractory lung metastasis from breast cancer treated with multidisciplinary therapy including an immunological approac
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Masahiro Takada Hiroshi Terunuma Xuewen Deng Md. Zahidunnabi Dewan Shigehira Saji Katsumasa Kuroi Naoki Yamamoto Masakazu Toi
- چاپ و سال / کشور: 2011
Description
suggestive case of metastatic disease from breast cancer is reported. The HER-2-positive tumor was refractory to several agents, including anti-HER-2 therapy, trastuzumab, and lapatinib. After re-induction of trastuzumab in combination with activated natural killer (NK) cell injection therapy, tumor markers decreased, and finally a synergistic effect of taxane and capecitabine led to treatment response. This case suggests that multidisciplinary therapy including an immunological approach might be a breakthrough in the treatment of refractory disease.
Breast Cancer (2011) 18:64–67 DOI 10.1007/s12282-010-0198-5 Received: 8 January 2009 / Accepted: 21 January 2010 / Published online: 31 March 2010 The Japanese Breast Cancer Society 2010