Comparing the Detectability of Hepatocellular Carcinomav by C-Arm Dual-Phase Cone-Beam Computed Tomography During Hepatic Arteriography With Conventional Contrast-Enhanced Magnetic Resonance Imaging
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Romaric Loffroy MingDe Lin Pramod Rao Nikhil Bhagat Niels Noordhoek Alessandro Radelli Ja¨rl Blijd Jean-Franc¸ois Geschwind
- چاپ و سال / کشور: 2011
Description
Purpose To evaluate the sensitivity of dual-phase conebeam computed tomography during hepatic arteriography (CBCTHA) for the detection of hepatocellular carcinoma (HCC) by comparing it with the diagnostic imaging ‘‘gold standard’’: contrast-enhanced magnetic resonance imaging (CE-MRI) of the liver. Materials and Methods Eighty-eight HCC lesions (mean diameter 3.9 ± 3.3 cm) in 20 patients (13 men, mean age 61.4 years [range 50 to 80]), who sequentially underwent baseline diagnostic liver CE-MRI and then underwent early arterial- and delayed portal venous-phase CBCTHA during drug eluting-bead transarterial chemoembolization, were evaluated. Dual-phase CBCTHA findings of each tumor in terms of conspicuity were compared with standard CE-MR images and classified into three grades: optimal, suboptimal, and nondiagnostic. Results Seventy-seven (mean diameter 4.2 ± 3.4 cm [range 0.9 to 15.9]) (93.9%) of 82 tumors were detected. Sensitivity of arterial-phase (71.9%) was lower than that of venous-phase CBCTHA (86.6%) for the detection of HCC lesions. Of the 82 tumors, 33 (40.2%) and 52 (63.4%), 26 (31.7%) and 19 (23.2%), and 23 (28%) and 11 (13.4%) nodules were classed as optimal, suboptimal, and nondiagnostic on arterial- and venous-phase CBCTHA images, respectively. Seventeen (73.9%) of the 23 tumors that were not visible on arterial phase were detected on venous phase. Six (54.5%) of the 11 tumors that were not visible on venous phase were detected on arterial phase. Conclusions Dual-phase CBCTHA has sufficient image quality to detect the majority of HCC lesions compared with the imaging ‘‘gold standard’’: CE-MRI of the liver. Moreover, dual-phase CBCTHA is more useful and reli
Cardiovasc Intervent Radiol Received: 1 October 2010 / Accepted: 24 January 2011
