Obscure manifestations of Salmonella subdural empyema in children: case report and literature review

Obscure manifestations of Salmonella subdural empyema in children: case report and literature review

  • نوع فایل : کتاب
  • زبان : انگلیسی
  • مؤلف : Kai-Mao Chen & Hsiu-Fen Lee & Ching-Shiang Chi & Fang-Liang Huang & Cheng-Yi Chang & Hao-Chun Hung
  • چاپ و سال / کشور: 2010

Description

Purpose Salmonella intracranial infections, including subdural empyema and brain abscess, are rare clinical manifestations in children. The aim of this study is to investigate the clinical course of Salmonella subdural empyema in infants and children. Methods We report a 9-month-old female infant diagnosed as Salmonella subdural empyema with clinical features of prolonged fever for more than 2 months and episodic focal seizures. Literature published between 1986 and 2010 relevant to Salmonella subdural empyema in children were reviewed. The clinical presentations and laboratory findings were analyzed. Results Seventeen cases with Salmonella subdural empyema, including our index case, has been reported with detailed clinical presentation. Fever (17/17; 100%), symptoms and signs of increased intracranial pressure (8/17; 47%), seizures (8/17; 47%), and limb paralysis (8/17; 47%) were the most frequent clinical features. Among these cases, unknown causative organism prior to surgery (11/17; 65%) and prolonged fever for more than 3 weeks (5/17; 29%) were also noticed. Sixteen out of 17 patients (94%) required surgical intervention for treatment. The morbidity rate and mortality rate were 29% (5/17) and 6% (1/17), respectively. Conclusion Subdural empyema is considered to be a disease with rapid progression. However, the cases caused by Salmonella species may present a slow disease course. Surgical intervention is sometimes the only way to detect the pathogen.
Hydrocephalus . Neuroendoscopy . Complication . Bone dust . Migration Received: 28 July 2010 / Accepted: 24 August 2010 / Published online: 7 September 2010
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