Time between first symptoms and diagnosis in patients with acute pulmonary embolism: are patients with recurrent episodes diagnosed earlier?
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Thomas M. Berghaus W. von Scheidt M. Schwaiblmair
- چاپ و سال / کشور: 2010
Description
Background Early diagnosis can be life-saving in acute pulmonary embolism (PE). It is unknown, whether patients with recurrent PE are diagnosed earlier than those with their first episode. Methods Admission data of patients with symptomatic acute PE were reviewed over a period of 47 months. Delay in diagnosis, demographics, body mass index, comorbidity, mortality, risk factors for venous thromboembolism and socio-economic status were recorded. Results 56 out of 248 patients had recurrent PE, 192 patients were hospitalized because of their first episode. Delay in diagnosis after symptom onset was significantly greater in patients with recurrent than in patients with their first PE (3.4 ± 2.3 vs. 2.2 ± 1.7 days, p = 0.006). Recurrent PE was significantly more often unprovoked (p\0.001); by contrast, preceding trauma or surgery were significantly (p = 0.007) more frequent in first PE. Conclusions Missing predisposing factors in unprovoked PE might explain the greater delay in diagnosis in recurrent PE. Physicians should focus more on informing patients about the possibility of PE recurrence and associated symptoms and thereby enable earlier diagnosis in recurrent PE.
Clin Res Cardiol (2011) 100:117–119 DOI 10.1007/s00392-010-0217-8' Received: 29 April 2010 / Accepted: 25 August 2010 / Published online: 6 September 2010
