Wasabi nose: an underreported complication of cyclophosphamide infusions
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Ginger L. Janow & Norman T. Ilowite & Dawn M. Wahezi
- چاپ و سال / کشور: 2011
Description
Wasabi nose, a term used to describe the nasopharyngeal discomfort experienced during cyclophosphamide infusions, is a rare phenomenon, previously described in case reports of adult oncology patients typically receiving high-dose chemotherapy regimens. The underlying mechanism by which this phenomenon occurs is unknown. We report four cases of children with rheumatic diseases afflicted by profound nasopharyngeal discomfort secondary to low-dose cyclophosphamide infusions. We additionally review the literature regarding potential medical management of these complications and describe our experience using these interventions.
Clin Rheumatol (2011) 30:1003–1005 Received: 24 January 2011 / Accepted: 24 February 2011 / Published online: 8 March 2011
