Cutaneous nodules in patients with rheumatoid arthritis: a case report and review of literatures
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Tadashi Nakamura & Syu-ichi Higashi & Kunihiko Tomoda & Michishi Tsukano & Ken-ichi Iyama
- چاپ و سال / کشور: 2011
Description
We report a case of 57-year-old Japanese woman with an overlap syndrome of both rheumatoid arthritis (RA) and autoimmune hepatitis, who developed multiple skin nodules. An extensive biopsies of the nodules revealed rheumatoid neutrophilic dermatitis, showing panniculitis without vasculitis, combining with granulomatous formation histopathologically. Since cutaneous nodules in patients with RA are very complex, differential diagnosis should be done according to disease activities, medications used, and pathological findings. We suggest that the differences in histopathological findings of cutaneous nodules in patients with RA depend on their immunological conditions based on disease activities including therapeutic effects.
Clin Rheumatol (2011) 30:719–722 Received: 25 September 2010 / Accepted: 8 October 2010 / Published online: 4 November 2010
