Nitric oxide metabolites status in calves with acute and chronic diarrhea
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : G. A. Kojouri & H. Hassanpour & N. Taghavi & C. Taghadosi
- چاپ و سال / کشور: 2011
Description
Neonatal diarrhea in calves causes intestinal inflammation that can lead to an increase in the concentration of some inflammatory mediators like nitric oxide in serum. In the presence of some molecules in biological fluids, nitric oxide sustains a series of reactions and produces nitrate and nitrite. Consequently, this paper has been done to determine if the serum levels of nitrite and nitrate can be a precise yardstick to evaluate the health condition of calves. Sixty calves in three groups (20 heads healthy as control group, 20 heads with chronic diarrhea, and 20 heads with acute diarrhea) were considered, and blood samples were collected to determine the concentration of nitrite and nitrate in serum by reducing by cadmium and evaluation of photo-absorbance by spectrophotometer. Results showed that in calves with acute diarrhea, the total concentration of nitrite and nitrate and the concentration of nitrate were significantly more than healthy calves and the calves with chronic diarrhea (P<0.001). In addition, a negative and significant correlation (r=-0.788, Pvalue= 0.0353) was observed between nitrite and nitrate concentration of healthy calves
Comp Clin Pathol DOI 10.1007/s00580-011-1275-7 Received: 29 December 2007 / Accepted: 8 June 2011
