Purinoceptors and Bladder Dysfunction
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Phillip P. Smith
- چاپ و سال / کشور: 2011
Description
Purinergic signaling is increasingly appreciated as an important contributor to the normal bladder functions of urine storage and voiding. The translation of disease and injury to abnormal sensory and motor function, resulting in lower urinary tract symptoms, is in part mediated by the interaction of adenosine 5پŒ-triphosphate and related purines with specific purinergic receptors (purinoceptors). Identification and clarification of purinoceptor-based processes are important research goals aimed at novel therapeutic targets for functional disorders inadequately served by standard therapies. This review presents an update on recent developments in the understanding of the purinoceptors and bladder dysfunction.
Curr Bladder Dysfunct Rep (2011) 6:85–92 DOI 10.1007/s11884-011-0081-z Published online: 8 February 2011
