Breast Preservation in Patients with Local Recurrence After Breast-Conserving Therapy
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Jessica Suarez & Douglas Arthur &Wendy Woodward & Henry M. Kuerer
- چاپ و سال / کشور: 2011
Description
Mastectomy is the current standard of care following in-breast local recurrence of breast cancer previously treated with breast-conserving surgery and whole-breast irradiation. Review of the limited world literature on repeat breast-conserving surgery suggests that the risk of secondary local in-breast recurrence may be too high in unselected patients following this approach. Rapid evolution of radiation therapy techniques has brought partial-breast irradiation (PBI) to the forefront as a potential local treatment for women with in-breast local recurrence following repeat breast-conserving surgery. This review gives an overview of the biological rationale for PBI; reviews techniques, potential benefits, and complications of PBI; and describes a new phase II national cooperative group trial evaluating PBI following repeat breastconserving surgery. Mastectomy may not be necessary in all patients with in-breast local recurrence of breast cancer.
Curr Breast Cancer Rep (2011) 3:88–96 DOI 10.1007/s12609-011-0042-8 Published online: 15 March 2011
