Who Benefits from Portal Vein Embolization Prior to Major Hepatectomy for Colorectal Cancer Liver Metastases?
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Eddie K. Abdalla
- چاپ و سال / کشور: 2011
Description
Preoperative portal vein embolization (PVE) is used to increase the volume and function of the liver that will remain after major hepatectomy (the future liver remnant, or FLR). This report summarizes evidence supporting the use of PVE in patients with colorectal liver metastases. The safe limits of resection define the indications for PVE based on underlying liver disease—the limit in patients with normal liver is 20% of the standardized total liver volume (TLV); with diseased liver, 30% of TLV; with compensated cirrhosis, 40% of TLV. PVE can convert an inadequate FLR to an FLR sufficient to ensure safe surgery, and the degree of FLR hypertrophy after PVE predicts post-resection liver function. PVE can be safely combined with chemotherapy, including biologic agents, without significant compromise to its efficacy.
Curr Colorectal Cancer Rep (2011) 7:152–160 DOI 10.1007/s11888-011-0094-1 Published online: 25 March 2011
