Molecular Markers of Chemotherapy Toxicity in Colorectal Cancer
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Michael S. Braun & Matthew T. Seymour
- چاپ و سال / کشور: 2010
Description
Personalized medicine appears to be the inevitable consequence of improvements in our understanding of the mechanisms of action of chemotherapeutic agents, as well as the description of the human genome and its impact on our understanding of the genes involved in DNA repair and drug metabolism. These rapid developments have been associated with the first efforts to establish genetic predictors of chemotherapy efficacy and toxicity for the chemotherapy drugs active in colorectal cancer—fluorouracil, irinotecan, and oxaliplatin.
Curr Colorectal Cancer Rep (2011) 7:105–111 DOI 10.1007/s11888-010-0078-6 Published online: 24 December 2010
